OBJECTIVE: The current study examined whether cognitive reactivity, cognitive extremity reactivity, and mood reactivity following mood provocation predicted relapse in depression over 5.5 years. Additionally, this study was the 1st to examine whether changes in cognitive reactivity and mood reactivity following preventive cognitive therapy (PCT) mediated the preventive effect of PCT on relapse. METHOD: One hundred eighty-seven remitted recurrently depressed outpatients were randomized over treatment as usual (TAU) versus TAU + PCT with 5.5-year follow-up. Relapse in depression was assessed with the Structured Clinical Interview for DSM-IV Axis I Disorders (Spitzer, Williams, Gibbon, & First, 1990). RESULTS: Mood reactivity predicted time to relapse over 5.5 years. We found no evidence that cognitive reactivity was a risk factor for relapse in depression. Moreover, unprimed dysfunctional beliefs predicted relapse directly. There was no indication of mediation by changes in cognitive reactivity (including extremity of the beliefs and unprimed beliefs) or mood reactivity on the preventive effect of PCT. Further, explorative analyses revealed that increases in cognitive and mood reactivity over time also predicted time to relapse. CONCLUSIONS: Our findings highlight a need to focus on mood reactivity instead of beliefs as a risk factor for relapse in depression. Similar to a previous study, we found no indications that cognitive therapy after remission reduced dysfunctional beliefs, cognitive reactivity, or extremity. Future studies should examine cognitive reactivity and mood reactivity in daily life as predictors of relapse.
RCT Entities:
OBJECTIVE: The current study examined whether cognitive reactivity, cognitive extremity reactivity, and mood reactivity following mood provocation predicted relapse in depression over 5.5 years. Additionally, this study was the 1st to examine whether changes in cognitive reactivity and mood reactivity following preventive cognitive therapy (PCT) mediated the preventive effect of PCT on relapse. METHOD: One hundred eighty-seven remitted recurrently depressed outpatients were randomized over treatment as usual (TAU) versus TAU + PCT with 5.5-year follow-up. Relapse in depression was assessed with the Structured Clinical Interview for DSM-IV Axis I Disorders (Spitzer, Williams, Gibbon, & First, 1990). RESULTS: Mood reactivity predicted time to relapse over 5.5 years. We found no evidence that cognitive reactivity was a risk factor for relapse in depression. Moreover, unprimed dysfunctional beliefs predicted relapse directly. There was no indication of mediation by changes in cognitive reactivity (including extremity of the beliefs and unprimed beliefs) or mood reactivity on the preventive effect of PCT. Further, explorative analyses revealed that increases in cognitive and mood reactivity over time also predicted time to relapse. CONCLUSIONS: Our findings highlight a need to focus on mood reactivity instead of beliefs as a risk factor for relapse in depression. Similar to a previous study, we found no indications that cognitive therapy after remission reduced dysfunctional beliefs, cognitive reactivity, or extremity. Future studies should examine cognitive reactivity and mood reactivity in daily life as predictors of relapse.
Authors: Gerard D van Rijsbergen; Claudi L H Bockting; Matthias Berking; Maarten W J Koeter; Aart H Schene Journal: PLoS One Date: 2012-10-03 Impact factor: 3.240
Authors: F Matcham; C Barattieri di San Pietro; V Bulgari; G de Girolamo; R Dobson; H Eriksson; A A Folarin; J M Haro; M Kerz; F Lamers; Q Li; N V Manyakov; D C Mohr; I Myin-Germeys; V Narayan; Penninx Bwjh; Y Ranjan; Z Rashid; A Rintala; S Siddi; S K Simblett; T Wykes; M Hotopf Journal: BMC Psychiatry Date: 2019-02-18 Impact factor: 3.630
Authors: Roel J T Mocking; Caroline A Figueroa; Maria M Rive; Hanneke Geugies; Michelle N Servaas; Johanna Assies; Maarten W J Koeter; Frédéric M Vaz; Marieke Wichers; Jan P van Straalen; Rudi de Raedt; Claudi L H Bockting; Catherine J Harmer; Aart H Schene; Henricus G Ruhé Journal: BMJ Open Date: 2016-03-01 Impact factor: 2.692
Authors: Caroline A Figueroa; Roel J T Mocking; Guido van Wingen; Suzanne Martens; Henricus G Ruhé; Aart H Schene Journal: Soc Cogn Affect Neurosci Date: 2017-11-01 Impact factor: 3.436
Authors: Caroline A Figueroa; Roel J T Mocking; Gelera A Mahmoud; Maarten W Koeter; Claudi L Bockting; Willem van der Does; Henricus G Ruhe; Aart H Schene Journal: Br J Clin Psychol Date: 2018-02-27
Authors: Cristina Senín-Calderón; Salvador Perona-Garcelán; Miguel Ruíz-Veguilla; Juan F Rodríguez-Testal Journal: Int J Clin Health Psychol Date: 2017-03-19
Authors: Margo de Jonge; Claudi L H Bockting; Patricia van Oppen; Henricus L Van; Jaap Peen; Martijn J Kikkert; Jack J M Dekker Journal: PLoS One Date: 2018-11-02 Impact factor: 3.240