Literature DB >> 2347677

Prognostic factors in childhood acute lymphoblastic leukaemia.

J Armstrong1, M Pomeroy, J J Fennelly, S Cahalane.   

Abstract

58 patients under the age of 14 years with acute lymphoblastic leukaemia were managed from 1971 to 1985. We analysed their overall survival from diagnosis to assess the prognostic significance of clinical and laboratory features present at diagnosis. Factors which were statistically significant included white blood count, platelet count, palpable lymph node enlargement, mediastinal widening on chest x-ray and palpable splenic enlargement. The purpose of this study was to identify that subset of patients which might have benefitted from more intensive treatment.

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Year:  1990        PMID: 2347677     DOI: 10.1007/bf02937246

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  28 in total

1.  Presence of clonal chromosome abnormalities in virtually all cases of acute lymphoblastic leukemia.

Authors:  D L Williams; S Raimondi; G Rivera; S George; C W Berard; S B Murphy
Journal:  N Engl J Med       Date:  1985-09-05       Impact factor: 91.245

2.  Management of childhood acute leukaemia.

Authors:  J J Fennelly; A McBride; S O'Donoghue; T M Kavanagh; S Cahalane
Journal:  Ir Med J       Date:  1974-11-23

Review 3.  Recent advances in the biology and treatment of acute lymphoblastic leukemia in adults.

Authors:  A D Jacobs; R P Gale
Journal:  N Engl J Med       Date:  1984-11-08       Impact factor: 91.245

4.  Improved survival from acute lymphoblastic leukemia in adolescents and adults.

Authors:  H A Blacklock; J R Matthews; J G Buchanan; P A Ockelford; R S Hill
Journal:  Cancer       Date:  1981-11-01       Impact factor: 6.860

5.  Cytogenetics of acute lymphoblastic leukaemia in children as a factor in the prediction of long-term survival.

Authors:  L M Secker-Walker; G J Swansbury; R M Hardisty; S E Sallan; O M Garson; M Sakurai; S D Lawler
Journal:  Br J Haematol       Date:  1982-11       Impact factor: 6.998

6.  Serum lactic dehydrogenase level has prognostic value in childhood acute lymphoblastic leukemia.

Authors:  C H Pui; R K Dodge; G V Dahl; G Rivera; A T Look; D Kalwinsky; W P Bowman; J Ochs; M Abromowitch; J Mirro
Journal:  Blood       Date:  1985-10       Impact factor: 22.113

7.  Elevated serum transaminase activity at diagnosis is associated with rapidly progressing disease in children with acute lymphoblastic leukemia.

Authors:  J Rautonen; M A Siimes
Journal:  Cancer       Date:  1988-02-15       Impact factor: 6.860

8.  Acute lymphoid leukemia in adolescents: clinical and biologic features predict a poor prognosis--a Pediatric Oncology Group Study.

Authors:  W Crist; J Pullen; J Boyett; J Falletta; J van Eys; M Borowitz; J Jackson; B Dowell; C Russell; F Quddus
Journal:  J Clin Oncol       Date:  1988-01       Impact factor: 44.544

9.  Initial features and prognosis in 363 children with acute lymphocytic leukemia.

Authors:  J V Simone; M S Verzosa; J A Rudy
Journal:  Cancer       Date:  1975-12       Impact factor: 6.860

10.  Sex and prognosis in childhood acute lymphoblastic leukaemia.

Authors:  J H Baumer; M G Mott
Journal:  Lancet       Date:  1978-07-15       Impact factor: 79.321

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