Literature DB >> 23475889

The tumor suppressor FAT1 modulates WNT activity in multiple cancers.

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Abstract

FAT1 is a tumor suppressor that is frequently mutated and inhibits WNT/β-catenin signaling.

Entities:  

Year:  2013        PMID： 23475889     DOI： 10.1158/2159-8290.CD-RW2013-031

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  3 in total

1.  POU2F1 promotes growth and metastasis of hepatocellular carcinoma through the FAT1 signaling pathway.

Authors:  Hong Yan Zhu; Guan Yi Cao; Shi Ping Wang; Yu Chen; Guo Dong Liu; Yu Jie Gao; Jian Ping Hu
Journal:  Am J Cancer Res       Date:  2017-08-01       Impact factor: 6.166

2.  Circulating Tumor Cell Enumeration and Characterization in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Cabazitaxel.

Authors:  Ingeborg E de Kruijff; Anieta M Sieuwerts; Wendy Onstenk; Jaco Kraan; Marcel Smid; Mai N Van; Michelle van der Vlugt-Daane; Esther Oomen-de Hoop; Ron H J Mathijssen; Martijn P Lolkema; Ronald de Wit; Paul Hamberg; Hielke J Meulenbeld; Aart Beeker; Geert-Jan Creemers; John W M Martens; Stefan Sleijfer
Journal:  Cancers (Basel)       Date:  2019-08-20       Impact factor: 6.639

3.  Favorable immune checkpoint inhibitor outcome of patients with melanoma and NSCLC harboring FAT1 mutations.

Authors:  Wenjing Zhang; Yunfeng Tang; Yuxian Guo; Yujia Kong; Fuyan Shi; Chao Sheng; Suzhen Wang; Qinghua Wang
Journal:  NPJ Precis Oncol       Date:  2022-06-23
  3 in total

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