| Literature DB >> 23474773 |
Fuwu Zhang1, Mahmoud Elsabahy, Shiyi Zhang, Lily Yun Lin, Jiong Zou, Karen L Wooley.
Abstract
Polymeric micelles and shell crosslinked knedel-like (SCK) nanoparticles were loaded with up to 48% (w/w) cisplatin. These spherical cisplatin-loaded nanoparticles displayed sustained platinum release over 5 days in PBS, enhanced stability over free cisplatin in aqueous milieu, and significant antitumor activity in vitro against two cancer cell lines.Entities:
Mesh:
Substances:
Year: 2013 PMID: 23474773 DOI: 10.1039/c3nr34320k
Source DB: PubMed Journal: Nanoscale ISSN: 2040-3364 Impact factor: 7.790