Literature DB >> 23474469

First enantioselective synthesis of tetracyclic intermediates en route to madangamine D.

Mercedes Amat1, Roberto Ballette, Stefano Proto, Maria Pérez, Joan Bosch.   

Abstract

The enantioselective synthesis of advanced tetracyclic precursors of madangamine D, bearing rings ABCD of this alkaloid, is reported. The saturated 14-membered ring is assembled from functionalized diazatricyclic intermediates following either ring-closing metathesis or macrolactamization strategies.

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Year:  2013        PMID: 23474469     DOI: 10.1039/c3cc41104d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  A New Organocatalytic Desymmetrization Reaction Enables the Enantioselective Total Synthesis of Madangamine E.

Authors:  Shinya Shiomi; Benjamin D A Shennan; Ken Yamazaki; Ángel L Fuentes de Arriba; Dhananjayan Vasu; Trevor A Hamlin; Darren J Dixon
Journal:  J Am Chem Soc       Date:  2022-01-17       Impact factor: 15.419

  1 in total

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