Literature DB >> 23474035

[Infantile hemangioma: update and treatment].

C Léauté-Labrèze1.   

Abstract

Infantile hemangioma (IH) is not strictly speaking a tumor, but the result of anarchic postnatal vasculogenesis. Hypoxia seems to play an important role as a predisposing factor. IHs can present three clinical morphologies: superficial, deep, or mixed. Localized IHs are oval or round, circumscribed lesions, whereas segmental IHs extend across a large anatomic area with a geographic shape. Localized IHs are often benign, except when they are located near a noble structure such as the airways or the orbital area. Segmental IH may be associated with birth defects (PHACES syndrome and SACRAL syndrome). Clinical follow-up of infants with IH should be very careful in the first weeks of life since 80% of all IHs have reached their final size at 5 months of age. The main indications for treatment of IHs are: life-threatening conditions (heart failure, respiratory distress), functional risks (amblyopia, swallowing disorders, etc.), aesthetic risks (especially IH of the face localized on the nose, lips, etc.), and painful ulcerated IH. Beta-blockers, namely propranolol, have quickly become the first-line therapy of complicated IH. The treatment should be given as soon as possible to avoid sequelae.
Copyright © 2013 Elsevier Masson SAS. All rights reserved.

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Year:  2013        PMID: 23474035     DOI: 10.1016/j.arcped.2013.01.052

Source DB:  PubMed          Journal:  Arch Pediatr        ISSN: 0929-693X            Impact factor:   1.180


  3 in total

Review 1.  Infantile Hemangioma: A Brief Review.

Authors:  Madalina Bota; Gheorghe Popa; Cristina Blag; Alexandru Tataru
Journal:  Clujul Med       Date:  2015-01-28

2.  Congenital liver hemangioma revealed by cholestasis syndrome: report of a rare case.

Authors:  Chaimae Khairoun; Amina Barkat
Journal:  Pan Afr Med J       Date:  2020-07-17

3.  Infantile hemangiomas: a 7-year experience of a single-center.

Authors:  Mădălina Bota; Gheorghe Popa; Cristina Lucia Blag; Daniel-Corneliu Leucuta; Alexandru Tătaru
Journal:  Clujul Med       Date:  2017-10-20
  3 in total

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