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Literature DB >> 2347398

The effect of guanethidine treatment of testicular blood flow and testosterone production in rats.

Abstract

Testicular blood flow was measured by means of Xenon-133 clearance in control rats and rats treated with guanethidine for 3 weeks. Plasma and testis testosterone concentrations were also measured, and the effect of hCG-treatment was examined. No difference in testicular blood flow between the control group and the guanethidine-treated group was found. However, in guanethidine-treated rats, plasma and testis testosterone concentrations after hCG-treatment were significantly decreased. The results may indicate that adrenergic nerves are involved in the regulation of Leydig cell function.

Entities: Chemical Gene Species

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Year: 1990 PMID： 2347398 DOI： 10.1007/bf01954240

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

13 in total

1. The effect of long-term variation in sympathetic activity on testicular morphology in immature rats.

Authors: A Bergh; H Blom; J E Damber; R Henriksson
Journal: Andrologia Date: 1987 Jul-Aug Impact factor: 2.775

2. Effect of catecholamines on porcine Sertoli and Leydig cells in primary culture.

Authors: G Renier; J Gaulin; W Gibb; R Collu; J R Ducharme
Journal: Can J Physiol Pharmacol Date: 1987-10 Impact factor: 2.273

3. Long-lasting damage to the internal male genital organs and their adrenergic innervation in rats following chronic treatment with the antihypertensive drug guanethidine.

Authors: B Evans; B J Gannon; J W Heath; G Burnstock
Journal: Fertil Steril Date: 1972-09 Impact factor: 7.329

1. Ultrastructural evidence of indirect and direct autonomic innervation of human Leydig cells: comparison of neonatal, childhood and pubertal ages.

Authors: F P Prince
Journal: Cell Tissue Res Date: 1992-09 Impact factor: 5.249

1 in total

The effect of guanethidine treatment of testicular blood flow and testosterone production in rats.

1. The effect of long-term variation in sympathetic activity on testicular morphology in immature rats.

2. Effect of catecholamines on porcine Sertoli and Leydig cells in primary culture.

3. Long-lasting damage to the internal male genital organs and their adrenergic innervation in rats following chronic treatment with the antihypertensive drug guanethidine.

4. The effect of epinephrine on testosterone production.

5. Prolonged effects of chronic guanethidine treatment on the sympathetic innervation of the genitalia of male rats.

6. Variation between species in the innervation of intra-testicular blood vessels.

7. Testicular blood flow measured with a laser Doppler flowmeter: acute effects of catecholamines.

8. Methodological aspects of testicular blood flow measurements in rats.

9. Blood flow in the testis of the conscious ram measured with krypton85.

10. Catecholamine stimulation of testosterone production via cyclic AMP in mouse Leydig cells in monolayer culture.

1. Ultrastructural evidence of indirect and direct autonomic innervation of human Leydig cells: comparison of neonatal, childhood and pubertal ages.