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Literature DB >> 2347394

Effect of L-carnitine and stimulated lipolysis on muscle substrates in the exercising rat.

Abstract

To test the effect of L-carnitine on glycogen sparing when fat oxidation is increased, 100 mg/kg/d were given to rats orally for 3 days, resulting in 1.8-fold higher muscle carnitine levels. Even when FFA were raised by heparin-stimulated lipolysis, the rate of glycogen degradation was not reduced during exercise.

Entities: Chemical Species

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Year: 1990 PMID： 2347394 DOI： 10.1007/bf01954228

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

13 in total

1. Depletion of muscle and liver glycogen during exercise. Protective effect of training.

Authors: K M Baldwin; R H Fitts; F W Booth; W W Winder; J O Holloszy
Journal: Pflugers Arch Date: 1975 Impact factor: 3.657

2. The effect of muscle extracts on the oxidation of palmitic acid by liver slices and homogenates.

Authors: I FRITZ
Journal: Acta Physiol Scand Date: 1955-10-12

3. Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles.

Authors: P J Randle; E A Newsholme; P B Garland
Journal: Biochem J Date: 1964-12 Impact factor: 3.857

4. Human forearm muscle metabolism during exercise. VII. FFA uptake and oxidation at different work intensities.

Authors: L Hagenfeldt; J Wahren
Journal: Scand J Clin Lab Invest Date: 1972-12 Impact factor: 1.713

5. Concentration of triglycerides, phospholipids and glycogen in skeletal muscle and of free fatty acids and beta-hydroxybutyric acid in blood in man in response to exercise.

Authors: L A Carlson; L G Ekelund; S O Fröberg
Journal: Eur J Clin Invest Date: 1971-01 Impact factor: 4.686

Effect of L-carnitine and stimulated lipolysis on muscle substrates in the exercising rat.

1. Depletion of muscle and liver glycogen during exercise. Protective effect of training.

2. The effect of muscle extracts on the oxidation of palmitic acid by liver slices and homogenates.

3. Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles.

4. Human forearm muscle metabolism during exercise. VII. FFA uptake and oxidation at different work intensities.

5. Concentration of triglycerides, phospholipids and glycogen in skeletal muscle and of free fatty acids and beta-hydroxybutyric acid in blood in man in response to exercise.

6. Exercise-induced ultrastructural changes in skeletal muscle.

7. Effects of increased plasma fatty acids on glycogen utilization and endurance.

8. Effects of acute moderate-intensity exercise on carnitine metabolism in men and women.

9. Muscle triglyceride utilization during exercise: effect of training.

Review 10. Carnitine--metabolism and functions.

1. Carnitine and physical exercise.