| Literature DB >> 2347374 |
M N Guilly1, J P Kolb, F Gosti, F Godeau, J C Courvalin.
Abstract
Lamins are major proteins of the nuclear envelope that are members of the intermediate filament protein family. In vertebrates, nuclei from differentiated tissues usually contain both lamins of the A and B subtypes, while embryonic tissues contain the B-type lamin only. We have examined the composition of the nuclear lamina in human B and T lymphocytes representative of distinct stages of lymphoid differentiation. We show here that, in both cell lineages, while lamin B is constitutively expressed at all stages of differentiation, A-type lamin expression is restricted to later developmental stages.Entities:
Mesh：
Substances：
Year: 1990 PMID： 2347374 DOI： 10.1016/0014-4827(90)90267-e
Source DB: PubMed Journal: Exp Cell Res ISSN： 0014-4827 Impact factor: 3.905