RATIONALE AND OBJECTIVES: To compare free-breathing three-dimensional (3D) phase-sensitive inversion recovery (PSIR) with breath-holding two-dimensional (2D) IR sequences to determine which is better for detecting and characterizing myocardial late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM) patients. MATERIALS AND METHODS:Thirty HCM patients clinically underwent 3.0 T cardiac magnetic resonance imaging that included 3D-PSIR and 2D-IR. The amount of LGE lesions was calculated and expressed as %LGE of the myocardial mass, and the average of the %LGE value reported by two observers was recorded as the final %LGE. We also counted the number of LGE lesions and recorded their location. The myocardium-LGE contrast, margin sharpness, artifacts, and overall image quality were graded on a 4-point grading scale (1 = poor, 2 = fair, 3 = good, 4 = excellent). RESULTS: The mean %LGE on 2D-IR was 24.7 ± 0.6, 17.5 ± 0.6, and 8.5 ± 0.3, respectively, for the basal, mid-, and apical myocardium; the corresponding values were 24.2 ± 0.4, 20.0 ± 0.4, and 7.7 ± 0.3 on 3D-PSIR (2D-IR versus 3D-PSIR, P = .87). On 2D IR and 3D-PSIR images, 13, 52, and 53, and 9, 74, and 33 LGE lesions were detected in the subendocardial, midwall, subepicardial area, respectively. The myocardium-LGE contrast and overall image quality were significantly higher on 3D-PSIR than 2D-IR images (P < .001); the sequences did not differ significantly with respect to margin sharpness and artifact. CONCLUSION: Three-dimensional PSIR sequence yields higher image contrast, better image quality, and greater detection ability for LGE lesions than 2D-IR sequence.
RCT Entities:
RATIONALE AND OBJECTIVES: To compare free-breathing three-dimensional (3D) phase-sensitive inversion recovery (PSIR) with breath-holding two-dimensional (2D) IR sequences to determine which is better for detecting and characterizing myocardial late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM) patients. MATERIALS AND METHODS: Thirty HCM patients clinically underwent 3.0 T cardiac magnetic resonance imaging that included 3D-PSIR and 2D-IR. The amount of LGE lesions was calculated and expressed as %LGE of the myocardial mass, and the average of the %LGE value reported by two observers was recorded as the final %LGE. We also counted the number of LGE lesions and recorded their location. The myocardium-LGE contrast, margin sharpness, artifacts, and overall image quality were graded on a 4-point grading scale (1 = poor, 2 = fair, 3 = good, 4 = excellent). RESULTS: The mean %LGE on 2D-IR was 24.7 ± 0.6, 17.5 ± 0.6, and 8.5 ± 0.3, respectively, for the basal, mid-, and apical myocardium; the corresponding values were 24.2 ± 0.4, 20.0 ± 0.4, and 7.7 ± 0.3 on 3D-PSIR (2D-IR versus 3D-PSIR, P = .87). On 2D IR and 3D-PSIR images, 13, 52, and 53, and 9, 74, and 33 LGE lesions were detected in the subendocardial, midwall, subepicardial area, respectively. The myocardium-LGE contrast and overall image quality were significantly higher on 3D-PSIR than 2D-IR images (P < .001); the sequences did not differ significantly with respect to margin sharpness and artifact. CONCLUSION: Three-dimensional PSIR sequence yields higher image contrast, better image quality, and greater detection ability for LGE lesions than 2D-IR sequence.
Authors: Martin Rajchl; John Stirrat; Maged Goubran; Jeff Yu; David Scholl; Terry M Peters; James A White Journal: Int J Cardiovasc Imaging Date: 2014-10-12 Impact factor: 2.357
Authors: M Polacin; I Kapos; M Gastl; C Blüthgen; M Karolyi; J von Spiczak; M Eberhard; B Baessler; H Alkadhi; S Kozerke; R Manka Journal: Int J Cardiovasc Imaging Date: 2020-08-13 Impact factor: 2.357