RATIONALE AND OBJECTIVES: The aim of this study is to assess the usefulness of computer-aided three-dimensional (3D) measurement of volume and computed tomography (CT) attenuation values of nodes for diagnosing nodal metastases of lung cancer. MATERIALS AND METHODS: We measured three diameters, their ratios, volume, and CT values in 3D images of 191 nodes (64 malignant; 162 of <1 cm in short diameter) in 26 consecutive patients who underwent contrast-enhanced, thin-section, multidetector row CT before surgery. We separately studied statistically significant factors in a group of all nodes and in another group of nodes of <1 cm in short diameter with logistic modeling and evaluated their diagnostic accuracy. RESULTS: Significant factors were CT values (P < .001) and short diameter (P = .001) for the total node group, and CT values (P = .030) and 3D volume (P = .035) for the <1 cm node group. Optimal 83% accuracy was obtained with a criterion of short diameter of >7.4 mm and CT values of >103 Hounsfield unit (HU) for the total node group, whereas optimal 76% accuracy was obtained with a criterion of 3D volume of >1282 mm(3) or CT values of >103 HU for the <1 cm node group. CONCLUSION: 3D measurement may be useful for diagnosing nodal metastases.
RATIONALE AND OBJECTIVES: The aim of this study is to assess the usefulness of computer-aided three-dimensional (3D) measurement of volume and computed tomography (CT) attenuation values of nodes for diagnosing nodal metastases of lung cancer. MATERIALS AND METHODS: We measured three diameters, their ratios, volume, and CT values in 3D images of 191 nodes (64 malignant; 162 of <1 cm in short diameter) in 26 consecutive patients who underwent contrast-enhanced, thin-section, multidetector row CT before surgery. We separately studied statistically significant factors in a group of all nodes and in another group of nodes of <1 cm in short diameter with logistic modeling and evaluated their diagnostic accuracy. RESULTS: Significant factors were CT values (P < .001) and short diameter (P = .001) for the total node group, and CT values (P = .030) and 3D volume (P = .035) for the <1 cm node group. Optimal 83% accuracy was obtained with a criterion of short diameter of >7.4 mm and CT values of >103 Hounsfield unit (HU) for the total node group, whereas optimal 76% accuracy was obtained with a criterion of 3D volume of >1282 mm(3) or CT values of >103 HU for the <1 cm node group. CONCLUSION: 3D measurement may be useful for diagnosing nodal metastases.
Authors: Alexandra F Belotta; Sally Sukut; Candace Lowe; Cheryl Waldner; Elissa K Randall; Valerie S MacDonald; Jerome Gagnon; Monique N Mayer Journal: Can J Vet Res Date: 2022-01 Impact factor: 0.897