Literature DB >> 23473660

The impact of stressful life events, symptom status, and adherence concerns on quality of life in people living with HIV.

Inge B Corless, Joachim Voss, A J Guarino, Dean Wantland, William Holzemer, Mary Jane Hamilton, Elizabeth Sefcik, Suzanne Willard, Kenn Kirksey, Carmen Portillo, Marta Rivero Mendez, Maria E Rosa, Patrice K Nicholas, Sarie Human, Mary Maryland, Shahnaz Moezzi, Linda Robinson, Yvette Cuca.   

Abstract

Studies concerning persons living with HIV (PLWH) report that stressful life events (SLEs) contribute to an exacerbation of symptoms and reduced antiretroviral (ARV) adherence and quality of life (QOL). Little is known about whether these findings are site-specific. Our study's aims were to characterize the type and frequency of SLEs for PLWH in Puerto Rico, South Africa, and the United States, and to assess the impact of SLEs by national site, symptoms, and ARV adherence concerns on QOL. The sample consisted of 704 participants. The total number of SLEs correlated significantly with the total number of symptoms, adherence concerns, and QOL (p ≤ .001). Overall, 27.2% of the variance in QOL was explained by the aforementioned variables. Although SLEs were of concern to PLWH, worries about ARV adherence were of even greater concern. Routine assessment of ARV concerns and SLEs can promote ongoing ARV adherence and improved QOL.
Copyright © 2013 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  HIV; adherence; quality of life; stressful life events; symptoms

Mesh:

Substances:

Year:  2013        PMID: 23473660      PMCID: PMC3681926          DOI: 10.1016/j.jana.2012.11.005

Source DB:  PubMed          Journal:  J Assoc Nurses AIDS Care        ISSN: 1055-3290            Impact factor:   1.354


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