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Literature DB >> 23473487

The nanomechanical properties of lipid membranes are significantly influenced by the presence of ethanol.

Abstract

Ethanol has a profound impact on biological systems and is moreover used in various medical and nonmedical applications. Its interaction with the lipid part of biological membranes has been the subject of intensive studies, but surprisingly, to our knowledge, no study has examined the influence of ethanol on lipid bilayer nanomechanics. We performed atomic force microscopy-based measurements to assess the influence of ethanol on the nanomechanical properties of fluid supported lipid bilayers. Ethanol significantly reduces membrane stability, bilayer thickness, Young's modulus, area stretch modulus, and bending stiffness. Altogether, our data suggest that ethanol addition to supported lipid bilayers supports both the hydrophobic and the hydrophilic permeation pathways by a decrease of bilayer thickness and reduced stability, respectively.

Entities: Chemical

Mesh：

Substances：
Liposomes
Ethanol

Year: 2013 PMID： 23473487 PMCID： PMC3870802 DOI： 10.1016/j.bpj.2013.01.021

Source DB: PubMed Journal: Biophys J ISSN： 0006-3495 Impact factor: 4.033

32 in total

1. Direct measurement of the mechanical properties of lipid phases in supported bilayers.

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2. High-resolution AFM of membrane proteins directly incorporated at high density in planar lipid bilayer.

Authors: Pierre-Emmanuel Milhiet; Francesca Gubellini; Alexandre Berquand; Patrice Dosset; Jean-Louis Rigaud; Christian Le Grimellec; Daniel Lévy
Journal: Biophys J Date: 2006-08-11 Impact factor: 4.033

3. Direct imaging of individual intrinsic hydration layers on lipid bilayers at Angstrom resolution.

Authors: Takeshi Fukuma; Michael J Higgins; Suzanne P Jarvis
Journal: Biophys J Date: 2007-02-26 Impact factor: 4.033

4. Bending and puncturing the influenza lipid envelope.

Authors: Sai Li; Frederic Eghiaian; Christian Sieben; Andreas Herrmann; Iwan A T Schaap
Journal: Biophys J Date: 2011-02-02 Impact factor: 4.033

5. Gramicidin channel kinetics under tension.

Authors: M Goulian; O N Mesquita; D K Fygenson; C Nielsen; O S Andersen; A Libchaber
Journal: Biophys J Date: 1998-01 Impact factor: 4.033

Review 6. Supported membranes: scientific and practical applications.

Authors: E Sackmann
Journal: Science Date: 1996-01-05 Impact factor: 47.728

7. Nuclear Overhauser enhancement spectroscopy cross-relaxation rates and ethanol distribution across membranes.

Authors: Scott E Feller; Christopher A Brown; David T Nizza; Klaus Gawrisch
Journal: Biophys J Date: 2002-03 Impact factor: 4.033

8. Effect of chain length and unsaturation on elasticity of lipid bilayers.

Authors: W Rawicz; K C Olbrich; T McIntosh; D Needham; E Evans
Journal: Biophys J Date: 2000-07 Impact factor: 4.033

Review 9. Surface plasmon resonance in protein-membrane interactions.

Authors: Mojca Besenicar; Peter Macek; Jeremy H Lakey; Gregor Anderluh
Journal: Chem Phys Lipids Date: 2006-03-20 Impact factor: 3.329

10. The influence of short-chain alcohols on interfacial tension, mechanical properties, area/molecule, and permeability of fluid lipid bilayers.

Authors: Hung V Ly; Marjorie L Longo
Journal: Biophys J Date: 2004-08 Impact factor: 4.033

17 in total

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5. Drunken Membranes: Short-Chain Alcohols Alter Fusion of Liposomes to Planar Lipid Bilayers.

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Journal: Biophys J Date: 2017-01-10 Impact factor: 4.033

6. The mechanobiology of actin cytoskeletal proteins during cell-cell fusion.

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7. Membrane Disruption Mechanism of a Prion Peptide (106-126) Investigated by Atomic Force Microscopy, Raman and Electron Paramagnetic Resonance Spectroscopy.

Authors: Jianjun Pan; Prasana K Sahoo; Annalisa Dalzini; Zahra Hayati; Chinta M Aryal; Peng Teng; Jianfeng Cai; Humberto Rodriguez Gutierrez; Likai Song
Journal: J Phys Chem B Date: 2017-05-10 Impact factor: 2.991