Literature DB >> 23472885

Analysis of protein aggregation in neurodegenerative disease.

Jeppe T Pedersen1, Niels H H Heegaard.   

Abstract

Pathological protein and peptide aggregation are key events in a number of chronic and devastating neurodegenerative conditions including dementias such as Alzheimer's and Creutzfeldt-Jakob's disease and other central nervous system diseases such as Parkinson's and Huntington's disease and amyotrophic lateral sclerosis. Analytical methods for studying protein aggregation in these diseases are important for mapping pathophysiological events and ultimately for the development of new therapies and better diagnostic tools.

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Year:  2013        PMID： 23472885     DOI： 10.1021/ac400023c

Source DB:  PubMed          Journal:  Anal Chem        ISSN： 0003-2700            Impact factor:   6.986


  21 in total

1.  Interaction of the polyglutamine protein ataxin-3 with Rad23 regulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3.

Authors:  Joanna R Sutton; Jessica R Blount; Kozeta Libohova; Wei-Ling Tsou; Gnanada S Joshi; Henry L Paulson; Maria do Carmo Costa; K Matthew Scaglione; Sokol V Todi
Journal:  Hum Mol Genet       Date:  2017-04-15       Impact factor: 6.150

2.  Ubiquitin-binding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23.

Authors:  Jessica R Blount; Wei-Ling Tsou; Gorica Ristic; Aaron A Burr; Michelle Ouyang; Holland Galante; K Matthew Scaglione; Sokol V Todi
Journal:  Nat Commun       Date:  2014-08-21       Impact factor: 14.919

Review 3.  Insulin Formulation Characterization-the Thioflavin T Assays.

Authors:  Morten Schlein
Journal:  AAPS J       Date:  2016-12-20       Impact factor: 4.009

Review 4.  In Silico Studies in Drug Research Against Neurodegenerative Diseases.

Authors:  Farahnaz Rezaei Makhouri; Jahan B Ghasemi
Journal:  Curr Neuropharmacol       Date:  2018       Impact factor: 7.363

5.  Detection of amyloid fibrils in Parkinson's disease using plasmonic chirality.

Authors:  Jatish Kumar; Hasier Eraña; Elena López-Martínez; Nathalie Claes; Víctor F Martín; Diego M Solís; Sara Bals; Aitziber L Cortajarena; Joaquín Castilla; Luis M Liz-Marzán
Journal:  Proc Natl Acad Sci U S A       Date:  2018-03-12       Impact factor: 11.205

6.  p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1.

Authors:  So-Yoon Won; Jung-Jin Park; Soon-Tae You; Jong-A Hyeun; Hyong-Kyu Kim; Byung Kwan Jin; Catriona McLean; Eun-Young Shin; Eung-Gook Kim
Journal:  Cell Death Dis       Date:  2022-06-30       Impact factor: 9.685

Review 7.  Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodies.

Authors:  Hao Zhang; Weidong Cui; Michael L Gross
Journal:  FEBS Lett       Date:  2013-11-26       Impact factor: 4.124

8.  AQAMAN, a bisamidine-based inhibitor of toxic protein inclusions in neurons, ameliorates cytotoxicity in polyglutamine disease models.

Authors:  Huiling Hong; Alex Chun Koon; Zhefan Stephen Chen; Yuming Wei; Ying An; Wen Li; Matthew Ho Yan Lau; Kwok-Fai Lau; Jacky Chi Ki Ngo; Chun-Ho Wong; Ho Yu Au-Yeung; Steven C Zimmerman; Ho Yin Edwin Chan
Journal:  J Biol Chem       Date:  2018-12-28       Impact factor: 5.157

9.  Plaque-associated lipids in Alzheimer's diseased brain tissue visualized by nonlinear microscopy.

Authors:  Juris Kiskis; Helen Fink; Lena Nyberg; Jacob Thyr; Jia-Yi Li; Annika Enejder
Journal:  Sci Rep       Date:  2015-08-27       Impact factor: 4.379

Review 10.  Atomic force microscopy as an advanced tool in neuroscience.

Authors:  Maja Jazvinšćak Jembrek; Goran Šimić; Patrick R Hof; Suzana Šegota
Journal:  Transl Neurosci       Date:  2015-06-11       Impact factor: 1.757
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