| Literature DB >> 23472866 |
Abstract
Although SOX2 has been identified as a squamous cell carcinoma oncogene, mechanisms of SOX2-induce oncogenesis have remained elusive. In this issue of Cell Stem Cell, Li et al. (2013) show that SOX2 synergizes with inflammation-induced STAT3 activation to transform basal progenitors and initiate squamous cell carcinoma.Entities:
Year: 2013 PMID: 23472866 DOI: 10.1016/j.stem.2013.02.004
Source DB: PubMed Journal: Cell Stem Cell ISSN: 1875-9777 Impact factor: 25.269