Literature DB >> 23472473

Anti-metastatic activities of bibenzyls from Dendrobium pulchellum.

Pithi Chanvorachote1, Akkarawut Kowitdamrong, Thidarat Ruanghirun, Boonchoo Sritularak, Chutichot Mungmee, Kittisak Likhitwitayawuid.   

Abstract

Our investigation of the stem of Dendrobium pulchellum resulted in the isolation of four known bibenzyls, chrysotobibenzyl (1), chrysotoxine (2), crepidatin (3) and moscatilin (4). The present study reveals for the first time the ability of these four compounds to facilitate anoikis and inhibit the growth of lung cancer cells in anchorage-independent condition. The preliminary data obtained disclose the inhibitory effect on cancer cell metastasis of the isolated compounds, and provide an important new approach for cancer drug development.

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Year:  2013        PMID： 23472473

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN： 1555-9475            Impact factor:   0.986


  10 in total

1.  A bibenzyl from Dendrobium ellipsophyllum inhibits migration in lung cancer cells.

Authors:  Chatchai Chaotham; Pithi Chanvorachote
Journal:  J Nat Med       Date:  2015-06-25       Impact factor: 2.343

2.  Moscatilin inhibits epithelial-to-mesenchymal transition and sensitizes anoikis in human lung cancer H460 cells.

Authors:  Kesarin Busaranon; Preeyaporn Plaimee; Boonchoo Sritularak; Pithi Chanvorachote
Journal:  J Nat Med       Date:  2015-09-18       Impact factor: 2.343

3.  Picrotoxane sesquiterpene and α-pyrone derivative from Dendrobium signatum and their free radical scavenging potency.

Authors:  Prajak Khumploy; Achara Raksat; Siwattra Choodej; Thammarat Aree; Nattaya Ngamrojanavanich; Khanitha Pudhom
Journal:  J Nat Med       Date:  2021-07-14       Impact factor: 2.343

4.  Cytotoxic and Antimigratory Activities of Phenolic Compounds from Dendrobium brymerianum.

Authors:  Pornprom Klongkumnuankarn; Kesarin Busaranon; Pithi Chanvorachote; Boonchoo Sritularak; Vichien Jongbunprasert; Kittisak Likhitwitayawuid
Journal:  Evid Based Complement Alternat Med       Date:  2015-01-15       Impact factor: 2.629

5.  Synthesis and Biological Evaluation of Novel Gigantol Derivatives as Potential Agents in Prevention of Diabetic Cataract.

Authors:  Jie Wu; Chuanjun Lu; Xue Li; Hua Fang; Wencheng Wan; Qiaohong Yang; Xiaosheng Sun; Meiling Wang; Xiaohong Hu; C-Y Oliver Chen; Xiaoyong Wei
Journal:  PLoS One       Date:  2015-10-30       Impact factor: 3.240

6.  Phoyunnanin E inhibits migration of non-small cell lung cancer cells via suppression of epithelial-to-mesenchymal transition and integrin αv and integrin β3.

Authors:  Nareerat Petpiroon; Boonchoo Sritularak; Pithi Chanvorachote
Journal:  BMC Complement Altern Med       Date:  2017-12-29       Impact factor: 3.659

7.  Artocarpin Targets Focal Adhesion Kinase-Dependent Epithelial to Mesenchymal Transition and Suppresses Migratory-Associated Integrins in Lung Cancer Cells.

Authors:  Nongyao Nonpanya; Kittipong Sanookpan; Nicharat Sriratanasak; Chanida Vinayanuwattikun; Duangdao Wichadakul; Boonchoo Sritularak; Pithi Chanvorachote
Journal:  Pharmaceutics       Date:  2021-04-14       Impact factor: 6.321

Review 8.  Anoikis-Associated Lung Cancer Metastasis: Mechanisms and Therapies.

Authors:  Jing Wang; Zhijie Luo; Lizhu Lin; Xinbing Sui; Lili Yu; Cong Xu; Ruonan Zhang; Ziming Zhao; Qianru Zhu; Bo An; Qiao Wang; Bi Chen; Elaine Lai-Han Leung; Qibiao Wu
Journal:  Cancers (Basel)       Date:  2022-09-30       Impact factor: 6.575

9.  Moscatilin inhibits lung cancer cell motility and invasion via suppression of endogenous reactive oxygen species.

Authors:  Akkarawut Kowitdamrong; Pithi Chanvorachote; Boonchoo Sritularak; Varisa Pongrakhananon
Journal:  Biomed Res Int       Date:  2013-05-08       Impact factor: 3.411

Review 10.  Dendrobium: Sources of Active Ingredients to Treat Age-Related Pathologies.

Authors:  Veronika Cakova; Frederic Bonte; Annelise Lobstein
Journal:  Aging Dis       Date:  2017-12-01       Impact factor: 6.745
  10 in total

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