Literature DB >> 23471990

Glia as primary drivers of neuropathology in TDP-43 proteinopathies.

Steven A Sloan1, Ben A Barres.   

Abstract

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Year:  2013        PMID： 23471990      PMCID： PMC3607032          DOI： 10.1073/pnas.1301608110

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  17 in total

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3.  Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

Authors:  Manuela Neumann; Deepak M Sampathu; Linda K Kwong; Adam C Truax; Matthew C Micsenyi; Thomas T Chou; Jennifer Bruce; Theresa Schuck; Murray Grossman; Christopher M Clark; Leo F McCluskey; Bruce L Miller; Eliezer Masliah; Ian R Mackenzie; Howard Feldman; Wolfgang Feiden; Hans A Kretzschmar; John Q Trojanowski; Virginia M-Y Lee
Journal:  Science       Date:  2006-10-06       Impact factor: 47.728

4.  Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis.

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5.  Transgenic-mouse model of amyotrophic lateral sclerosis.

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6.  Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.

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7.  Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.

Authors:  Francesco Paolo Di Giorgio; Gabriella L Boulting; Samuel Bobrowicz; Kevin C Eggan
Journal:  Cell Stem Cell       Date:  2008-12-04       Impact factor: 24.633

8.  TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia.

Authors:  Haixin Zhang; Chun-Feng Tan; Fumiaki Mori; Kunikazu Tanji; Akiyoshi Kakita; Hitoshi Takahashi; Koichi Wakabayashi
Journal:  Acta Neuropathol       Date:  2007-09-05       Impact factor: 17.088

9.  A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity.

Authors:  Brian S Johnson; J Michael McCaffery; Susan Lindquist; Aaron D Gitler
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-23       Impact factor: 11.205

10.  Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.

Authors:  D R Rosen; T Siddique; D Patterson; D A Figlewicz; P Sapp; A Hentati; D Donaldson; J Goto; J P O'Regan; H X Deng
Journal:  Nature       Date:  1993-03-04       Impact factor: 49.962
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Review 1.  Neuropathological Mechanisms of β-N-Methylamino-L-Alanine (BMAA) with a Focus on Iron Overload and Ferroptosis.

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Review 2.  Pathomechanisms of TDP-43 in neurodegeneration.

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3.  Temporal course of neurodegenerative effects on cognition in old age.

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Review 4.  The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what could be the mechanisms involved?

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6.  Astrocytes with TDP-43 inclusions exhibit reduced noradrenergic cAMP and Ca2+ signaling and dysregulated cell metabolism.

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7.  Identification of Genetic Modifiers of TDP-43: Inflammatory Activation of Astrocytes for Neuroinflammation.

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Review 8.  Pathophysiology of Lipid Droplets in Neuroglia.

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