Literature DB >> 23471330

An outbreak of forty five cases of Pseudomonas aeruginosa acute endophthalmitis after phacoemulsification.

Ricardo Luz Leitão Guerra1, Bruno de Paula Freitas, Cintia Maria Felix Medrado Parcero, Otacílio de Oliveira Maia, Roberto Lorens Marback.   

Abstract

PURPOSE: To describe an outbreak of Pseudomonas aeruginosa endophthalmitis post cataract surgery. Clinical findings, treatment and outcome are discussed.
METHODS: Clinical charts review of forty-five patients treated for endophthalmitis in a two-day period. The patients underwent primary vitrectomy, anterior chamber irrigation and intravitreous antibiotic injection. Cultures from vitreous and anterior chamber samples were performed in all patients.
RESULTS: Forty-five patients (twenty-three men and twenty-two women) were identified. The average age was 71.2 years (range, 56-83 years). The right eye (62%) was affected more often than the left eye (38%). The median interval between surgery and endophthalmitis onset was 5.5 days (range, 5-6 days). The visual acuity at the diagnosis was better than 20/40 in one patient (2%), from 20/40 to 20/200 in one patient (2%), from 20/400 to counting fingers in two patients (4%), hand movements in eleven patients (24%), and light perception in thirty patients (68%). Pseudomonas aeruginosa was the isolated agent in twenty-six vitreous samples and in three anterior chamber samples. Overall, one patient (2%) achieved a final visual acuity better than 20/40; eight patients (18%) achieved a final visual acuity from 20/40 to 20/200; six patients (13%) achieved a final visual acuity from 20/400 to counting fingers; eleven patients (25%) achieved a final acuity of hand movements; thirteen patients (29%) achieved a final acuity of light perception and six (13%) patients had no light perception at the last examination. None of these eyes underwent evisceration or enucleation in a three-month follow-up period.
CONCLUSION: Even with all the safety that cataract surgery has achieved, today, endophthalmitis remains a risk and a fearful complication of this procedure. In the present study, it was impossible to identify the source of the outbreak.

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Year:  2012        PMID: 23471330     DOI: 10.1590/s0004-27492012000500010

Source DB:  PubMed          Journal:  Arq Bras Oftalmol        ISSN: 0004-2749            Impact factor:   0.872


  4 in total

Review 1.  Antimicrobial guide to posterior segment infections.

Authors:  Tapan P Patel; David N Zacks; Vaidehi S Dedania
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2020-11-06       Impact factor: 3.117

2.  Post-cataract surgery cluster endophthalmitis due to multidrug-resistant Pseudomonas aeruginosa: A retrospective cohort study of six clusters.

Authors:  Swapnil M Parchand; Deepanshu Agrawal; Samrat Chatterjee; Anil Gangwe; Mihir Mishra; Deepshikha Agrawal
Journal:  Indian J Ophthalmol       Date:  2020-07       Impact factor: 1.848

3.  Outbreak of postoperative endophthalmitis caused by Pseudomonas aeruginosa: a case report and brief literature review.

Authors:  Kasra Cheraqpour; Aliasghar Ahmadraji; Seyed Ali Tabatabaei; Bahram Bohrani Sefidan; Mohammad Soleimani; Mansoor Shahriari; Bahareh Ramezani
Journal:  J Int Med Res       Date:  2021-11       Impact factor: 1.671

4.  Antibiotic sensitivity trends of pseudomonas endophthalmitis in a tertiary eye care center in South India: A 12-year retrospective study.

Authors:  Utsab Pan; Aarti Jain; Joseph Gubert; Bibha Kumari; Manavi D Sindal
Journal:  Indian J Ophthalmol       Date:  2020-04       Impact factor: 1.848

  4 in total

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