Literature DB >> 23471056

Blockbuster dreams for Pfizer's CDK inhibitor.

Malini Guha.   

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Year:  2013        PMID: 23471056     DOI: 10.1038/nbt0313-187a

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN: 1087-0156            Impact factor:   54.908


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  20 in total

1.  Pfizer's CDK4/6 inhibitor approved for advanced breast cancer.

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Review 3.  The other side of the coin: the tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND-CDK4/6-RB axis.

Authors:  Xiaomin Lou; Ju Zhang; Siqi Liu; Ningzhi Xu; D Joshua Liao
Journal:  Cell Cycle       Date:  2014-05-05       Impact factor: 4.534

Review 4.  Exploiting senescence for the treatment of cancer.

Authors:  Liqin Wang; Lina Lankhorst; René Bernards
Journal:  Nat Rev Cancer       Date:  2022-03-03       Impact factor: 69.800

5.  7SK small nuclear RNA inhibits cancer cell proliferation through apoptosis induction.

Authors:  Farid Keramati; Ehsan Seyedjafari; Parviz Fallah; Masoud Soleimani; Hossein Ghanbarian
Journal:  Tumour Biol       Date:  2014-12-10

6.  The CDK4/CDK6 inhibitor PD0332991 paradoxically stabilizes activated cyclin D3-CDK4/6 complexes.

Authors:  Sabine Paternot; Bianca Colleoni; Xavier Bisteau; Pierre P Roger
Journal:  Cell Cycle       Date:  2014       Impact factor: 4.534

7.  Direct interactions with both p27 and Cdk2 regulate Spy1-mediated proliferation in vivo and in vitro.

Authors:  Mohammad Al Sorkhy; Bre-Anne Fifield; Dorothy Myers; Lisa A Porter
Journal:  Cell Cycle       Date:  2016       Impact factor: 4.534

8.  Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases.

Authors:  Ernst Schonbrunn; Stephane Betzi; Riazul Alam; Mathew P Martin; Andreas Becker; Huijong Han; Rawle Francis; Ramappa Chakrasali; Sudhakar Jakkaraj; Aslamuzzaman Kazi; Said M Sebti; Christopher L Cubitt; Anthony W Gebhard; Lori A Hazlehurst; Joseph S Tash; Gunda I Georg
Journal:  J Med Chem       Date:  2013-05-06       Impact factor: 7.446

9.  Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor.

Authors:  T K Albert; C Rigault; J Eickhoff; K Baumgart; C Antrecht; B Klebl; G Mittler; M Meisterernst
Journal:  Br J Pharmacol       Date:  2014-01       Impact factor: 8.739

Review 10.  The molecular balancing act of p16(INK4a) in cancer and aging.

Authors:  Kyle M LaPak; Christin E Burd
Journal:  Mol Cancer Res       Date:  2013-10-17       Impact factor: 5.852

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