Literature DB >> 23470739

Identification of a nitric oxide generation-stimulative principle in Scutellariae radix.

Ziyang Chen1, Kenichi Nihei, Hideyuki Tanaka, Yasushi Uda, Yukihito Kabuyama.   

Abstract

Scutellariae radix (SR, from the roots of Scutellaria baicalensis Georgi) is thought to regulate blood pressure. In this study, HPLC-based purification coupled with MS, NMR analysis revealed that baicalin, a major flavone in SR, stimulates endothelial NO generation, suggesting its potential as an ingredient in medicinal food and beverage to treat hypertension.

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Year:  2013        PMID： 23470739     DOI： 10.1271/bbb.120800

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  3 in total

Review 1.  Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II.

Authors:  M Akhtar Anwar; Sara S Al Disi; Ali H Eid
Journal:  Front Pharmacol       Date:  2016-03-08       Impact factor: 5.810

2.  Natural Deep Eutectic Solvent Extraction of Flavonoids of Scutellaria baicalensis as a Replacement for Conventional Organic Solvents.

Authors:  Wim Wouter Oomen; Paloma Begines; Natali Rianika Mustafa; Erica G Wilson; Robert Verpoorte; Young Hae Choi
Journal:  Molecules       Date:  2020-01-31       Impact factor: 4.411

3.  NMDA receptor-mediated neuroprotective effect of the Scutellaria baicalensis Georgi extract on the excitotoxic neuronal cell death in primary rat cortical cell cultures.

Authors:  Jinsong Yang; Xiaohong Wu; Haogang Yu; Xinbiao Liao; Lisong Teng
Journal:  ScientificWorldJournal       Date:  2014-05-21
  3 in total

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