Literature DB >> 23470160

Effect of radio frequency waves of electromagnetic field on the tubulin.

Mousavi Taghi1, Riazi Gholamhosein, Rezayi-Zarchi Saeed.   

Abstract

Microtubules (MTs) are macromolecular structures consisting of tubulin heterodimers and present in almost every eukaryotic cell. MTs fulfill all conditions for generation of electromagnetic field and are electrically polar due to the electrical polarity of a tubulin heterodimer. The calculated static electric dipole moment of about 1000 Debye makes them capable of being aligned parallel to the applied electromagnetic field direction. In the present study, the tubulin heterodimers were extracted and purified from the rat brains. MTs were obtained by polymerization in vitro. Samples of microtubules were adsorbed in the absence and in the presence of electromagnetic fields with radio frequency of 900 Hz. Our results demonstrate the effect of electromagnetic field with 900 Hz frequency to change the structure of MTs. In this paper, a related patent was used that will help to better understand the studied subject.

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Year:  2013        PMID: 23470160     DOI: 10.2174/18722148113079990007

Source DB:  PubMed          Journal:  Recent Pat Endocr Metab Immune Drug Discov        ISSN: 1872-2148


  5 in total

1.  Noninvasive radiofrequency treatment effect on mitochondria in pancreatic cancer cells.

Authors:  Steven A Curley; Flavio Palalon; Xiaolin Lu; Nadezhda V Koshkina
Journal:  Cancer       Date:  2014-07-01       Impact factor: 6.860

Review 2.  Searching for the perfect wave: the effect of radiofrequency electromagnetic fields on cells.

Authors:  Lisa Gherardini; Gastone Ciuti; Selene Tognarelli; Caterina Cinti
Journal:  Int J Mol Sci       Date:  2014-03-27       Impact factor: 5.923

3.  The effects of non-invasive radiofrequency treatment and hyperthermia on malignant and nonmalignant cells.

Authors:  Steven A Curley; Flavio Palalon; Kelly E Sanders; Nadezhda V Koshkina
Journal:  Int J Environ Res Public Health       Date:  2014-09-03       Impact factor: 3.390

4.  Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a two-centre German cohort trial with systematic comparison and effect-to-treatment analysis.

Authors:  Sergey V Roussakow
Journal:  BMJ Open       Date:  2017-11-03       Impact factor: 2.692

5.  Pre-exposure to 50 Hz-electromagnetic fields enhanced the antiproliferative efficacy of 5-fluorouracil in breast cancer MCF-7 cells.

Authors:  Qi Han; Rui Chen; Fangjie Wang; Sha Chen; Xiongshan Sun; Xiao Guan; Yao Yang; Bingjie Peng; Xiaodong Pan; Jinfang Li; Weijing Yi; Peng Li; Hongwei Zhang; Dongfang Feng; An Chen; Xiaohui Li; Shuhui Li; Zuoming Yin
Journal:  PLoS One       Date:  2018-04-04       Impact factor: 3.240

  5 in total

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