Literature DB >> 2346912

Intratumoral heterogeneity of DNA content in lung cancer.

F A Carey1, D Lamb, C C Bird.   

Abstract

Heterogeneity of DNA content was analyzed in 208 samples from 20 resected lung tumors. Only one carcinoma was homogeneously diploid, but the others had DNA aneuploidy in at least some tissue samples. Eighteen tumors (90%) had varying degrees of heterogeneity of DNA content. Over half of these could have been mislabeled as diploid if the tumors had not been widely sampled. The importance of adequate sampling in assessing ploidy status of lung tumors is emphasized.

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Year:  1990        PMID： 2346912     DOI： 10.1002/1097-0142(19900515)65:10<2266::aid-cncr2820651018>3.0.co;2-r

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  7 in total

Review 1.  The study of endocrine tumors by flow and image cytometry.

Authors:  Ingrid Zbieranowski; David Murray
Journal:  Endocr Pathol       Date:  1992-06       Impact factor: 3.943

2.  Importance of sampling method in DNA analysis of lung cancer.

Authors:  F A Carey; D Lamb; C C Bird
Journal:  J Clin Pathol       Date:  1990-10       Impact factor: 3.411

3.  DNA index, cellular proliferative activity and nucleolar organizer regions in cancers of the larynx.

Authors:  J Cappiello; P Nicolai; A R Antonelli; F Facchetti; M Cadei; A Cornacchiari; P G Grigolato
Journal:  Eur Arch Otorhinolaryngol       Date:  1995       Impact factor: 2.503

4.  Interphase nucleolar organiser regions and survival in squamous cell carcinoma of the bronchus: a 10 year follow up study of 138 cases.

Authors:  D A Boldy; J G Ayres; J Crocker; J A Waterhouse; M Gilthorpe
Journal:  Thorax       Date:  1991-12       Impact factor: 9.139

5.  [Intratumoral heterogeneity of DNA content in lung adenocarcinoma].

Authors:  H Miura; O Taira; S Hiraguri; M Hagiwara; H Kato
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  1998-08

6.  Progression and survival in prostatic adenocarcinoma: a comparison of clinical stage, Gleason grade, S-phase fraction and DNA ploidy.

Authors:  S Vesalainen; S Nordling; P Lipponen; M Talja; K Syrjänen
Journal:  Br J Cancer       Date:  1994-08       Impact factor: 7.640

7.  Comparative DNA analysis by image cytometry and flow cytometry in non-small cell lung cancer.

Authors:  T Yamamoto; H Horiguchi; H Kamma; M Noro; T Ogata; Y Inage; E Akaogi; K Mitsui; M Hori; M Isobe
Journal:  Jpn J Cancer Res       Date:  1994-11
  7 in total

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