Literature DB >> 2346911

Immunohistochemical evaluation of squamous cell carcinoma antigen and S-100 protein-positive cells in human malignant esophageal tissues.

H Matsuda1, M Mori, S Tsujitani, S Ohno, H Kuwano, K Sugimachi.   

Abstract

Localization and intensity of squamous cell carcinoma-related antigen (SCC-Ag) and infiltration of Langerhans' cells (LC) were investigated immunohistochemically, using anti-SCC-Ag and anti-S-100 protein antisera, respectively, in 36 cases of squamous cell carcinoma of the human esophagus. The SCC-Ag was an indicator of histologic differentiation of squamous cell carcinoma but not of malignant potential. The population density of LC correlated well with the histologic stage, vessel invasion, and postoperative survival time. In patients with a marked infiltration of LC, survival time was longer than for those in whom the infiltration was slight (P less than 0.05). The density of the LC can serve an indicator of defense of the host against the carcinoma. There was no correlation between SCC-Ag and S-100 protein-positive cells.

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Year:  1990        PMID： 2346911     DOI： 10.1002/1097-0142(19900515)65:10<2261::aid-cncr2820651017>3.0.co;2-8

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  10 in total

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2.  CD83(+) dendritic cells and Foxp3(+) regulatory T cells in primary lesions and regional lymph nodes are inversely correlated with prognosis of gastric cancer.

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Journal:  Gastric Cancer       Date:  2011-11-15       Impact factor: 7.370

3.  Cellular distribution and clinical value of urokinase-type plasminogen activator, its receptor, and plasminogen activator inhibitor-2 in esophageal squamous cell carcinoma.

Authors:  H Shiomi; Y Eguchi; T Tani; M Kodama; T Hattori
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4.  Heparanase expression, degradation of basement membrane and low degree of infiltration by immunocytes correlate with invasion and progression of human gastric cancer.

Authors:  Zun-Jiang Xie; Ying Liu; Li-Min Jia; Ye-Chun He
Journal:  World J Gastroenterol       Date:  2008-06-28       Impact factor: 5.742

5.  Tobacco smoke condensate cutaneous carcinogenesis: changes in Langerhans' cells and tumour regression.

Authors:  N A Zeid; H K Muller
Journal:  Int J Exp Pathol       Date:  1995-02       Impact factor: 1.925

Review 6.  Immunologic function of dendritic cells in esophageal cancer.

Authors:  Wenfeng Yang; Jinming Yu
Journal:  Dig Dis Sci       Date:  2007-12-13       Impact factor: 3.199

7.  Langerhans cells in cutaneous tumours: immunohistochemistry study using a computer image analysis system.

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Journal:  J Mol Histol       Date:  2006-11-02       Impact factor: 3.156

8.  Detection of lymph node metastasis of oesophageal cancer by RT-nested PCR for SCC antigen gene mRNA.

Authors:  M Kano; Y Shimada; J Kaganoi; T Sakurai; Z Li; F Sato; G Watanabe; M Imamura
Journal:  Br J Cancer       Date:  2000-01       Impact factor: 7.640

9.  Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma.

Authors:  Junying Chen; Desheng Yao; Yue Li; Hong Chen; Chanjuan He; Nan Ding; Yan Lu; Tingyu Ou; Shan Zhao; Li Li; Fengyi Long
Journal:  Int J Mol Med       Date:  2013-06-21       Impact factor: 4.101

10.  CD1a-positive infiltrating-dendritic cell density and 5-year survival from human breast cancer.

Authors:  B J Coventry; J Morton
Journal:  Br J Cancer       Date:  2003-08-04       Impact factor: 7.640
  10 in total

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