Omar Javery1, Paul Shyn, Koenraad Mortele. 1. Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. ojavery@partners.org
Abstract
OBJECTIVE: Assess the impact of FDG-PET or PET/CT (PI) on pancreatic cancer management when added to CT or MRI (CDI). MATERIALS AND METHODS: Forty-nine patients underwent 79 PI exams. Discordant findings on PI and CDI were assessed for clinical impact. RESULTS: Fifteen of 79 PI-CDI pairs were discordant. Ten of 79 PI favorably and 5 of 79 unfavorably altered management. PI favorably altered management more often when ordered for therapy monitoring compared to staging [risk ratio 13.00 (95% CI 1.77-95.30)] or restaging [risk ratio 18.5 (95% CI 2.50-137.22)]. CONCLUSION: PI favorably alters management more often when used for therapy monitoring compared to staging or restaging.
OBJECTIVE: Assess the impact of FDG-PET or PET/CT (PI) on pancreatic cancer management when added to CT or MRI (CDI). MATERIALS AND METHODS: Forty-nine patients underwent 79 PI exams. Discordant findings on PI and CDI were assessed for clinical impact. RESULTS: Fifteen of 79 PI-CDI pairs were discordant. Ten of 79 PI favorably and 5 of 79 unfavorably altered management. PI favorably altered management more often when ordered for therapy monitoring compared to staging [risk ratio 13.00 (95% CI 1.77-95.30)] or restaging [risk ratio 18.5 (95% CI 2.50-137.22)]. CONCLUSION: PI favorably alters management more often when used for therapy monitoring compared to staging or restaging.
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