Literature DB >> 23465303

In patients with severe sepsis, does a single dose of etomidate to facilitate intubation increase mortality?

Benton R Hunter1, Jonathan Kirschner.   

Abstract

Currently, single-dose etomidate has not been shown to cause increased mortality in septic patients requiring intubation; however, sufficiently powered randomized trials are required before definitive conclusions can be drawn.

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Year:  2013        PMID： 23465303     DOI： 10.1016/j.annemergmed.2012.12.024

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN： 0196-0644            Impact factor:   5.721


  2 in total

1.  Etomidate in sepsis: understanding the dilemma.

Authors:  David J Gagnon; David B Seder
Journal:  J Thorac Dis       Date:  2015-10       Impact factor: 2.895

2.  The neurosteroid 5β-pregnan-3α-ol-20-one enhances actions of etomidate as a positive allosteric modulator of α1β2γ2L GABAA receptors.

Authors:  P Li; J R Bracamontes; B D Manion; S Mennerick; J H Steinbach; A S Evers; G Akk
Journal:  Br J Pharmacol       Date:  2014-12       Impact factor: 8.739
  2 in total

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