OBJECTIVE: To determine the impact of the European Randomized Study of Screening for Prostate Cancer (ERSPC) publication in 2009 on prostate-specific antigen (PSA) level testing by Dutch general practitioners (GPs) in men aged ≥40 years. MATERIALS AND METHODS:Retrospective study with a Dutch insurance company database (containing PSA test claims) and a large district hospital-laboratory database (containing PSA-test results). The difference in primary PSA-testing rate as well as follow-up testing before and after the ERSPC was tested using the chi-square test with statistical significance at P < 0.05. RESULTS: Decline in PSA tests 4 months after ERSPC publication, especially for men aged ≥60 years. Primary testing as well as follow-up testing decreased, both for PSA levels of <4 ng/mL as well as for PSA levels of 4-10 ng/mL. Follow-up testing after a PSA level result of >10 ng/mL moderately increased (P = 0.171). Referral to a urologist after a PSA level result of >4 ng/mL decreased slightly after the ERSPC publication (P = 0.044). CONCLUSIONS: After the ERSPC publication primary PSA testing as well as follow-up testing decreased. Follow-up testing seemed not to be adequate after an abnormal PSA result. The reasons for this remain unclear.
RCT Entities:
OBJECTIVE: To determine the impact of the European Randomized Study of Screening for Prostate Cancer (ERSPC) publication in 2009 on prostate-specific antigen (PSA) level testing by Dutch general practitioners (GPs) in men aged ≥40 years. MATERIALS AND METHODS: Retrospective study with a Dutch insurance company database (containing PSA test claims) and a large district hospital-laboratory database (containing PSA-test results). The difference in primary PSA-testing rate as well as follow-up testing before and after the ERSPC was tested using the chi-square test with statistical significance at P < 0.05. RESULTS: Decline in PSA tests 4 months after ERSPC publication, especially for men aged ≥60 years. Primary testing as well as follow-up testing decreased, both for PSA levels of <4 ng/mL as well as for PSA levels of 4-10 ng/mL. Follow-up testing after a PSA level result of >10 ng/mL moderately increased (P = 0.171). Referral to a urologist after a PSA level result of >4 ng/mL decreased slightly after the ERSPC publication (P = 0.044). CONCLUSIONS: After the ERSPC publication primary PSA testing as well as follow-up testing decreased. Follow-up testing seemed not to be adequate after an abnormal PSA result. The reasons for this remain unclear.
Authors: S Lebentrau; M May; O Maurer; M Schostak; M Lehsnau; T Ecke; S Al-Dumaini; S Hallmann; A M Ahmed; V Braun; A Haferkamp; R M Bauer; C G Stief; D Baumunk; B Hoschke; H-P Braun; C Schäfer; M Hipp; J Maurer; K-P Braun; I Wolff; S Brookman-May; C Gilfrich Journal: Urologe A Date: 2014-05 Impact factor: 0.639
Authors: Sanny Kappen; Geertruida H de Bock; Eunice Sirri; Claudia Vohmann; Joachim Kieschke; Alexander Winter Journal: Front Oncol Date: 2021-05-28 Impact factor: 6.244
Authors: Robin W M Vernooij; Lyubov Lytvyn; Hector Pardo-Hernandez; Loai Albarqouni; Carlos Canelo-Aybar; Karen Campbell; Thomas Agoritsas Journal: BMJ Open Date: 2018-09-05 Impact factor: 2.692