Literature DB >> 23464520

Microvascular complications and diabetic retinopathy: recent advances and future implications.

Megha Barot1, Mitan R Gokulgandhi, Sulabh Patel, Ashim K Mitra.   

Abstract

Retinal microvascular alterations have been observed during diabetic retinopathy (DR) due to the retinal susceptibility towards subtle pathological alterations. Therefore, retinal microvascular pathology is essential to understand the nature of retinal degenerations during DR. In this review, the role of retinal microvasculature complications during progression of DR, along with recent efforts to normalize such alterations for better therapeutic outcome, will be underlined. In addition, current therapeutics and future directions for advancement of standard treatment for DR patients will be discussed.

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Year:  2013        PMID： 23464520      PMCID： PMC3840430          DOI： 10.4155/fmc.12.206

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


  133 in total

1.  Inhibition of experimental choroidal neovascularization by overexpression of tissue inhibitor of metalloproteinases-3 in retinal pigment epithelium cells.

Authors:  T Takahashi; T Nakamura; A Hayashi; M Kamei; M Nakabayashi; A A Okada; N Tomita; Y Kaneda; Y Tano
Journal:  Am J Ophthalmol       Date:  2000-12       Impact factor: 5.258

2.  Inhibition of angiogenesis by adenovirus-mediated sFlt-1 expression in a rat model of corneal neovascularization.

Authors:  C M Lai; M Brankov; T Zaknich; Y K Lai; W Y Shen; I J Constable; I Kovesdi; P E Rakoczy
Journal:  Hum Gene Ther       Date:  2001-07-01       Impact factor: 5.695

3.  Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin.

Authors:  K Mori; A Ando; P Gehlbach; D Nesbitt; K Takahashi; D Goldsteen; M Penn; C T Chen; K Mori; M Melia; S Phipps; D Moffat; K Brazzell; G Liau; K H Dixon; P A Campochiaro
Journal:  Am J Pathol       Date:  2001-07       Impact factor: 4.307

4.  Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo.

Authors:  S M Galbraith; D J Chaplin; F Lee; M R Stratford; R J Locke; B Vojnovic; G M Tozer
Journal:  Anticancer Res       Date:  2001 Jan-Feb       Impact factor: 2.480

5.  Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization.

Authors:  H Ozaki; M S Seo; K Ozaki; H Yamada; E Yamada; N Okamoto; F Hofmann; J M Wood; P A Campochiaro
Journal:  Am J Pathol       Date:  2000-02       Impact factor: 4.307

6.  Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization.

Authors:  K Mori; E Duh; P Gehlbach; A Ando; K Takahashi; J Pearlman; K Mori; H S Yang; D J Zack; D Ettyreddy; D E Brough; L L Wei; P A Campochiaro
Journal:  J Cell Physiol       Date:  2001-08       Impact factor: 6.384

7.  Experimental subretinal neovascularization is inhibited by adenovirus-mediated soluble VEGF/flt-1 receptor gene transfection: a role of VEGF and possible treatment for SRN in age-related macular degeneration.

Authors:  M Honda; T Sakamoto; T Ishibashi; H Inomata; H Ueno
Journal:  Gene Ther       Date:  2000-06       Impact factor: 5.250

8.  Anti-angiogenic cues from vascular basement membrane collagen.

Authors:  P C Colorado; A Torre; G Kamphaus; Y Maeshima; H Hopfer; K Takahashi; R Volk; E D Zamborsky; S Herman; P K Sarkar; M B Ericksen; M Dhanabal; M Simons; M Post; D W Kufe; R R Weichselbaum; V P Sukhatme; R Kalluri
Journal:  Cancer Res       Date:  2000-05-01       Impact factor: 12.701

9.  Cell injury unmasks a latent proangiogenic phenotype in mice with increased expression of FGF2 in the retina.

Authors:  H Yamada; E Yamada; N Kwak; A Ando; A Suzuki; N Esumi; D J Zack; P A Campochiaro
Journal:  J Cell Physiol       Date:  2000-10       Impact factor: 6.384

10.  Calcium dobesilate: pharmacological profile related to its use in diabetic retinopathy.

Authors:  P Berthet; J C Farine; J P Barras
Journal:  Int J Clin Pract       Date:  1999-12       Impact factor: 2.503
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  32 in total

1.  Novel thermosensitive pentablock copolymers for sustained delivery of proteins in the treatment of posterior segment diseases.

Authors:  Sulabh P Patel; Ravi Vaishya; Xiaoyan Yang; Dhananjay Pal; Ashim K Mitra
Journal:  Protein Pept Lett       Date:  2014       Impact factor: 1.890

Review 2.  From pathobiology to the targeting of pericytes for the treatment of diabetic retinopathy.

Authors:  Joseph F Arboleda-Velasquez; Cammi N Valdez; Christina K Marko; Patricia A D'Amore
Journal:  Curr Diab Rep       Date:  2015-02       Impact factor: 4.810

3.  Negative effects of transthyretin in high myopic vitreous on diabetic retinopathy.

Authors:  Jun Shao; Yong Yao
Journal:  Int J Ophthalmol       Date:  2017-12-18       Impact factor: 1.779

Review 4.  Exploring the molecular role of endostatin in diabetic neuropathy.

Authors:  Tuhin Mukherjee; Tapan Behl; Aayush Sehgal; Saurabh Bhatia; Harmanpreet Singh; Simona Bungau
Journal:  Mol Biol Rep       Date:  2021-02-09       Impact factor: 2.316

5.  Danhong Huayu Koufuye combined with metformin attenuated diabetic retinopathy in Zucker diabetic fatty rats.

Authors:  Wen-Pei Chen; Yan-Dong Wang; Yan Ma; Zi-Yang Zhang; Lu-Yun Hu; Jun-Li Lin; Bao-Qin Lin
Journal:  Int J Ophthalmol       Date:  2015-12-18       Impact factor: 1.779

Review 6.  Effects of Propolis Extract and Propolis-Derived Compounds on Obesity and Diabetes: Knowledge from Cellular and Animal Models.

Authors:  Hiroshi Kitamura
Journal:  Molecules       Date:  2019-12-01       Impact factor: 4.411

Review 7.  The Protective Effects of Neurotrophins and MicroRNA in Diabetic Retinopathy, Nephropathy and Heart Failure via Regulating Endothelial Function.

Authors:  Sergey Shityakov; Michiaki Nagai; Süleyman Ergün; Barbara M Braunger; Carola Y Förster
Journal:  Biomolecules       Date:  2022-08-12

8.  Repression of retinal microvascular endothelial cells by transthyretin under simulated diabetic retinopathy conditions.

Authors:  Jun Shao; Yong Yao
Journal:  Int J Ophthalmol       Date:  2016-06-18       Impact factor: 1.779

9.  Poly(ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors Reduce Reactive Gliosis and Improve Angiostatin Levels in Retina of Diabetic Rats.

Authors:  Mykhailo M Guzyk; Artem A Tykhomyrov; Victor S Nedzvetsky; Irina V Prischepa; Tatiana V Grinenko; Lesya V Yanitska; Tamara M Kuchmerovska
Journal:  Neurochem Res       Date:  2016-06-02       Impact factor: 3.996

Review 10.  Association of plasminogen activator inhibitor-1 4G5G Polymorphism with risk of diabetic nephropathy and retinopathy: a systematic review and meta-analysis.

Authors:  Seyed Alireza Dastgheib; Farzaneh Najafi; Ahmad Shajari; Reza Bahrami; Fatemeh Asadian; Jalal Sadeghizadeh-Yazdi; Elahe Akbarian; Seyed Alireza Emarati; Hossein Neamatzadeh
Journal:  J Diabetes Metab Disord       Date:  2020-11-03
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