Literature DB >> 23462216

Adipokines and vascular health in treated HIV infection: an obesity paradox?

Chris T Longenecker1, Whitney Dunn, Ying Jiang, Sara M Debanne, Grace A McComsey.   

Abstract

We examined the relationship between plasma adipokine concentrations and ultrasound measures of vascular health in 100 HIV-infected adults on antiretroviral therapy. Leptin was positively correlated with flow-mediated dilation of the brachial artery and negatively with carotid intima-media thickness. These relationships were independent of traditional risk factors and trunk fat in women but not men. Neither adiponectin nor resistin was associated with either measure of vascular health.

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Year:  2013        PMID： 23462216      PMCID： PMC4140858          DOI： 10.1097/QAD.0b013e3283606c11

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  22 in total

Review 1.  Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascular Medicine.

Authors:  James H Stein; Claudia E Korcarz; R Todd Hurst; Eva Lonn; Christopher B Kendall; Emile R Mohler; Samer S Najjar; Christopher M Rembold; Wendy S Post
Journal:  J Am Soc Echocardiogr       Date:  2008-02       Impact factor: 5.251

2.  Metabolic and cardiovascular complications in HIV-infected patients: new challenges for a new age.

Authors:  Rajesh T Gandhi; Paul E Sax; Steven K Grinspoon
Journal:  J Infect Dis       Date:  2012-06       Impact factor: 5.226

Review 3.  Leptin and cardiovascular disease: response to therapeutic interventions.

Authors:  Kwang Kon Koh; Sang Min Park; Michael J Quon
Journal:  Circulation       Date:  2008-06-24       Impact factor: 29.690

4.  Relationship of body composition, metabolic status, antiretroviral use, and HIV disease factors to endothelial dysfunction in HIV-infected subjects.

Authors:  Michael P Dubé; Changyu Shen; Kieren J Mather; Jeff Waltz; Martha Greenwald; Samir K Gupta
Journal:  AIDS Res Hum Retroviruses       Date:  2010-08       Impact factor: 2.205

5.  Leptin and adiponectin, but not IL18, are related with insulin resistance in treated HIV-1-infected patients with lipodystrophy.

Authors:  Sergi Veloso; Xavier Escoté; Victòria Ceperuelo-Mallafré; Miguel López-Dupla; Joaquim Peraire; Consuelo Viladés; Pere Domingo; Antoni Castro; Montserrat Olona; Joan-Josep Sirvent; Manuel Leal; Joan Vendrell; Cristóbal Richart; Francesc Vidal
Journal:  Cytokine       Date:  2012-02-24       Impact factor: 3.861

6.  Regional fat deposition and cardiovascular risk in HIV infection: the FRAM study.

Authors:  Jordan E Lake; David Wohl; Rebecca Scherzer; Carl Grunfeld; Phyllis C Tien; Stephen Sidney; Judith S Currier
Journal:  AIDS Care       Date:  2011-06-24

7.  Vitamin D supplementation and endothelial function in vitamin D deficient HIV-infected patients: a randomized placebo-controlled trial.

Authors:  Chris T Longenecker; Corrilynn O Hileman; Teresa L Carman; Allison C Ross; Shabnam Seydafkan; Todd T Brown; Danielle E Labbato; Norma Storer; Vin Tangpricha; Grace A McComsey
Journal:  Antivir Ther       Date:  2011-11-17

8.  Pericardial and thoracic peri-aortic adipose tissues contribute to systemic inflammation and calcified coronary atherosclerosis independent of body fat composition, anthropometric measures and traditional cardiovascular risks.

Authors:  Chun-Ho Yun; Tin-Yu Lin; Yih-Jer Wu; Chuan-Chuan Liu; Jen-Yuan Kuo; Hung-I Yeh; Fei-Shih Yang; Su-Chiu Chen; Charles Jia-Yin Hou; Hiram G Bezerra; Chung-Lieh Hung; Ricardo C Cury
Journal:  Eur J Radiol       Date:  2011-02-21       Impact factor: 3.528

9.  Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and men.

Authors:  Robert C Kaplan; Lawrence A Kingsley; Stephen J Gange; Lorie Benning; Lisa P Jacobson; Jason Lazar; Kathryn Anastos; Phyllis C Tien; A Richey Sharrett; Howard N Hodis
Journal:  AIDS       Date:  2008-08-20       Impact factor: 4.177

10.  Preclinical atherosclerosis due to HIV infection: carotid intima-medial thickness measurements from the FRAM study.

Authors:  Carl Grunfeld; Joseph A C Delaney; Christine Wanke; Judith S Currier; Rebecca Scherzer; Mary L Biggs; Phyllis C Tien; Michael G Shlipak; Stephen Sidney; Joseph F Polak; Daniel O'Leary; Peter Bacchetti; Richard A Kronmal
Journal:  AIDS       Date:  2009-09-10       Impact factor: 4.177
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  4 in total

1.  Leptin, Adiponectin and Cognition in Middle-aged HIV-infected and Uninfected Women. The Brooklyn Women's Interagency HIV Study.

Authors:  Deborah R Gustafson; Michelle M Mielke; Sheila A Keating; Susan Holman; Howard Minkoff; Howard A Crystal
Journal:  J Gerontol Geriatr Res       Date:  2015-09-23

2.  Chronic Exposure to HIV-Derived Protein Tat Impairs Endothelial Function via Indirect Alteration in Fat Mass and Nox1-Mediated Mechanisms in Mice.

Authors:  Laszlo Kovacs; Thiago Bruder-Nascimento; Lindsey Greene; Simone Kennard; Eric J Belin de Chantemèle
Journal:  Int J Mol Sci       Date:  2021-10-12       Impact factor: 5.923

3.  Stroke incidence is highest in women and non-Hispanic blacks living with HIV in the AIDS Clinical Trials Group Longitudinal Linked Randomized Trials cohort.

Authors:  Felicia C Chow; Michael R Wilson; Kunling Wu; Ronald J Ellis; Ronald J Bosch; Benjamin P Linas
Journal:  AIDS       Date:  2018-06-01       Impact factor: 4.632

4.  HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor-Dependent Increases in NADPH Oxidase 1 (Nox1), C-C Chemokine Receptor Type 5 (CCR5), and Inflammation.

Authors:  Thiago Bruder-Nascimento; Taylor C Kress; Simone Kennard; Eric J Belin de Chantemèle
Journal:  J Am Heart Assoc       Date:  2020-10-02       Impact factor: 5.501
  4 in total

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