Literature DB >> 23461840

Successful treatment of radiation-induced proctitis pain by blockade of the ganglion impar in an elderly patient with prostate cancer: a case report.

Ankur Khosla1, Oludayo Adeyefa, Syed Nasir.   

Abstract

OBJECTIVE: Chronic rectal pain secondary to radiation-induced proctitis is fast-becoming a leading cause of chronic pain, especially for prostate cancer survivors. Currently, many elderly patients resort to increased opioid intake to alleviate the pain. However, this increase in opioid consumption often leads to constipation and further aggravates the anorectal pain, thus leading to a perpetual, vicious cycle. We reasoned that blocking the ganglion impar could attenuate this sympathetically maintained pain, which would lead to a reduction in the consumption of opioids, lessen constipation, and lead to an improvement in the patient's quality of life. STUDY
DESIGN: Case report.
SETTING: An academic tertiary pain management clinic.
RESULTS: The authors report the case of a 73-year-old African American man with a history of prostate cancer who presented to the pain management clinic for evaluation and treatment of his chronic anorectal pain secondary to radiation-induced proctitis. The patient underwent a ganglion impar block, using the transcoccygeal technique, and consequently reported excellent pain relief with little or no use for opioid pain medications at a 2-month follow-up. Ultimately, this approach led to improved mobility and an increase in the patient's quality of life.
CONCLUSIONS: Based on this case's success, a prospective study or randomized control trial evaluating the efficacy of the ganglion impar block as a treatment option for chronic anorectal pain secondary to radiation-induced proctitis appears warranted. Wiley Periodicals, Inc.

Entities:  

Mesh:

Year:  2013        PMID: 23461840     DOI: 10.1111/pme.12065

Source DB:  PubMed          Journal:  Pain Med        ISSN: 1526-2375            Impact factor:   3.750


  5 in total

Review 1.  Radiotherapy-Specific Chronic Pain Syndromes in the Cancer Population: An Evidence-Based Narrative Review.

Authors:  Jay Karri; Laura Lachman; Alex Hanania; Anuj Marathe; Mani Singh; Nicholas Zacharias; Vwaire Orhurhu; Amitabh Gulati; Alaa Abd-Elsayed
Journal:  Adv Ther       Date:  2021-02-11       Impact factor: 3.845

2.  MR-guided perineural injection of the ganglion impar: technical considerations and feasibility.

Authors:  David R Marker; Paweena U-Thainual; Tamas Ungi; Aaron J Flammang; Gabor Fichtinger; Iulian I Iordachita; John A Carrino; Jan Fritz
Journal:  Skeletal Radiol       Date:  2016-01-20       Impact factor: 2.199

Review 3.  Evidence-based Clinical Practice Guidelines for Interventional Pain Management in Cancer Pain.

Authors:  Sushma Bhatnagar; Maynak Gupta
Journal:  Indian J Palliat Care       Date:  2015 May-Aug

4.  Transcoccygeal neurolytic ganglion impar block for perineal pain: A case series.

Authors:  K B Nalini; Shivakumar Shivanna; M S Vishnu; C V R Mohan
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2018 Oct-Dec

5.  Factors associated with Successful Responses to Ganglion Impar Block: A Retrospective Study.

Authors:  Chan-Sik Kim; Kyounghwan Jang; Jeong-Gil Leem; Jin-Woo Shin; Doo-Hwan Kim; Seong-Soo Choi
Journal:  Int J Med Sci       Date:  2021-06-11       Impact factor: 3.738

  5 in total

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