| Literature DB >> 23458237 |
Wen-Bo Zhao1, Shinpei Nakagawa, Atsushi Kato, Isao Adachi, Yue-Mei Jia, Xiang-Guo Hu, George W J Fleet, Francis X Wilson, Graeme Horne, Akihide Yoshihara, Ken Izumori, Chu-Yi Yu.
Abstract
A general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are precursors of various azepane iminosugars.Entities:
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Year: 2013 PMID： 23458237 DOI： 10.1021/jo400130p
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354