Literature DB >> 23457138

Characteristics of the Chlamydia trachomatis species - immunopathology and infections.

Irena Choroszy-Król Choroszy-Król1, Magdalena Frej-Mądrzak, Agnieszka Jama-Kmiecik, Tamara Bober, Jolanta Jolanta Sarowska.   

Abstract

Chlamydiae are microorganisms exhibiting characteristics intermediate between bacteria and viruses. Chlamydia is widespread in the natural world, intracellular parasites of people and animals. They are capable of independent reproduction, because they do not synthesize ATP, in its development cycle using the host cell metabolic pathways. The life cycle of these microorganisms is original, unique among bacteria and lasts from 24 to 48 hours. Chlamydia antigens consist of 4 groups: group-specific, species-specific, type-specific and subspecies-specific. The group of species-specific antigens consists of MOMP and heat shock proteins. C. trachomatis is a potent immunogen, stimulating the immune processes of microorganisms. In the course of C. trachomatis infection, the response mechanisms involved are: non-specific, specific, humoral and cellular. Chronic infection is characterized by maintenance of microorganisms in the host cell. Inflammation is formed in less time and with increased intensity and has a rapid immune response on the part of previously sensitized lymphocytes. C. trachomatis infections are the most common bacterial sexually-transmitted infections. It represents an important clinical problem for doctors in many areas of medicine such as dermatology, venereology, ophthalmology, gynecology and obstetrics, rheumatology and others. Chlamydial infections are important pathogens in medical practice, not only because they cause disease in various fields of medicine, but also because of the large proportion of the population suffering and exposed to these microbial infections. Chlamydial infections are characterized by multifocality and polymorphism changes. Chlamydia causes inflammation in the adult urethra and cervix with the possibility of serious complications, and can cause perinatal infections in infants.

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Year:  2012        PMID: 23457138

Source DB:  PubMed          Journal:  Adv Clin Exp Med        ISSN: 1899-5276            Impact factor:   1.727


  5 in total

Review 1.  Significant roles played by IL-10 in Chlamydia infections.

Authors:  Hamid Hakimi; Mohammad Zare-Bidaki; Nahid Zainodini; Shokrollah Assar; Mohammad Kazemi Arababadi
Journal:  Inflammation       Date:  2014-06       Impact factor: 4.092

2.  Influence of different delivery modes on the clinical characteristics of Chlamydia trachomatis pneumonia.

Authors:  Jiejing Xu; Lili Yu; Baidi Fu; Deyu Zhao; Feng Liu
Journal:  Eur J Pediatr       Date:  2018-05-31       Impact factor: 3.183

3.  Pathology after Chlamydia trachomatis infection is driven by nonprotective immune cells that are distinct from protective populations.

Authors:  Rebeccah S Lijek; Jennifer D Helble; Andrew J Olive; Kyra W Seiger; Michael N Starnbach
Journal:  Proc Natl Acad Sci U S A       Date:  2018-02-09       Impact factor: 11.205

4.  High prevalence of hpv multiple genotypes in women with persistent chlamydia trachomatis infection.

Authors:  Silva Seraceni; Manola Comar; Francesco De Seta; Claudia Colli; Rossella Del Savio; Giuliano Pesel; Valentina Zanin; Pierlanfranco D'Agaro; Carlo Contini
Journal:  Infect Agent Cancer       Date:  2014-09-08       Impact factor: 2.965

Review 5.  The role of intracellular organisms in the pathogenesis of inflammatory arthritis.

Authors:  Animesh Singh; Sarah Karrar
Journal:  Int J Inflam       Date:  2014-06-05
  5 in total

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