Literature DB >> 23456700

The mechanism of tissue-restricted antigen gene expression by AIRE.

Kristina Zumer1, Kalle Saksela, B Matija Peterlin.   

Abstract

The autoimmune regulator is a critical transcription factor for generating central tolerance in the thymus. Recent studies have revealed how the autoimmune regulator targets many otherwise tissue-restricted Ag genes to enable negative selection of autoreactive T cells.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23456700     DOI： 10.4049/jimmunol.1203210

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  17 in total

Review 1.  Periodontal and other oral manifestations of immunodeficiency diseases.

Authors:  M E Peacock; R M Arce; C W Cutler
Journal:  Oral Dis       Date:  2016-10-10       Impact factor: 3.511

2.  Bromodomain-containing protein 4-independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB.

Authors:  Fang Huang; Wei Shao; Koh Fujinaga; B Matija Peterlin
Journal:  J Biol Chem       Date:  2018-02-20       Impact factor: 5.157

3.  The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: A modeling investigation.

Authors:  Tina M Mitre; Massimo Pietropaolo; Anmar Khadra
Journal:  Math Biosci       Date:  2016-10-17       Impact factor: 2.144

Review 4.  AIRE expands: new roles in immune tolerance and beyond.

Authors:  Mark S Anderson; Maureen A Su
Journal:  Nat Rev Immunol       Date:  2016-03-14       Impact factor: 53.106

5.  FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator).

Authors:  Wei Shao; Kristina Zumer; Koh Fujinaga; B Matija Peterlin
Journal:  J Biol Chem       Date:  2016-06-30       Impact factor: 5.157

6.  Gene Polymorphisms for Both Auto-antigen and Immune-Modulating Proteins Are Associated with the Susceptibility of Autoimmune Myasthenia Gravis.

Authors:  Hai-Feng Li; Yu Hong; Xu Zhang; Yanchen Xie; Geir Olve Skeie; Hong-Jun Hao; Nils Erik Gilhus; Bing Liang; Yao-Xian Yue; Xian-Jun Zhang; Xiang Gao; Qi Wang; Zhe Gao; Xiao-Jun Ding; Min Song
Journal:  Mol Neurobiol       Date:  2016-08-08       Impact factor: 5.590

Review 7.  Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction.

Authors:  Noëlla Lopes; Arnauld Sergé; Pierre Ferrier; Magali Irla
Journal:  Front Immunol       Date:  2015-07-20       Impact factor: 7.561

8.  The Attenuated Live Yellow Fever Virus 17D Infects the Thymus and Induces Thymic Transcriptional Modifications of Immunomodulatory Genes in C57BL/6 and BALB/C Mice.

Authors:  Breno Luiz Melo-Lima; Danillo Lucas Alves Espósito; Benedito Antônio Lopes da Fonseca; Luiz Tadeu Moraes Figueiredo; Philippe Moreau; Eduardo Antonio Donadi
Journal:  Autoimmune Dis       Date:  2015-09-17

Review 9.  Human APECED; a Sick Thymus Syndrome?

Authors:  T Petteri Arstila; Hanna Jarva
Journal:  Front Immunol       Date:  2013-10-07       Impact factor: 7.561

10.  Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases.

Authors:  Taishin Akiyama; Miho Shinzawa; Junwen Qin; Nobuko Akiyama
Journal:  Front Immunol       Date:  2013-08-26       Impact factor: 7.561
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.