Cocaine-associated multifocal tics.

Of 4 patients with cocaine-induced multifocal tics, 2 had Tourette's syndrome and had a severe exacerbation of their symptoms. One of these 2 patients experienced the exacerbation following her 1st exposure to the drug; the 2nd, a habitual cocaine snorter, after smoking "crack" for the 1st time. The other 2 patients were habitual cocaine abusers who, following a binge with high doses of cocaine, experienced new-onset tics.