Literature DB >> 23455789

Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient.

Sushma Patra1, Mukul Vij, B Sukanya, Dharmesh Kapoor.   

Abstract

Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported in literature. We report a case of MMF-induced colitis with Graft versus Host Disease-like features, to highlight the importance of high clinical suspicion for its diagnosis, and that appropriate management in such a setting can reduce morbidity and mortality. We also review the relevant literature.

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Year:  2012        PMID: 23455789     DOI: 10.4103/0377-4929.107792

Source DB:  PubMed          Journal:  Indian J Pathol Microbiol        ISSN: 0377-4929            Impact factor:   0.740


  3 in total

1.  NIH Consensus development project on criteria for clinical trials in chronic graft-versus-host disease: II. The 2014 Pathology Working Group Report.

Authors:  Howard M Shulman; Diana M Cardona; Joel K Greenson; Sangeeta Hingorani; Thomas Horn; Elisabeth Huber; Andreas Kreft; Thomas Longerich; Thomas Morton; David Myerson; Victor G Prieto; Avi Rosenberg; Nathaniel Treister; Kay Washington; Mirjana Ziemer; Steven Z Pavletic; Stephanie J Lee; Mary E D Flowers; Kirk R Schultz; Madan Jagasia; Paul J Martin; Georgia B Vogelsang; David E Kleiner
Journal:  Biol Blood Marrow Transplant       Date:  2015-01-29       Impact factor: 5.742

2.  Recipient pretransplant inosine monophosphate dehydrogenase activity in nonmyeloablative hematopoietic cell transplantation.

Authors:  Meagan J Bemer; Linda J Risler; Brian R Phillips; Joanne Wang; Barry E Storer; Brenda M Sandmaier; Haichuan Duan; Brianne S Raccor; Michael J Boeckh; Jeannine S McCune
Journal:  Biol Blood Marrow Transplant       Date:  2014-06-09       Impact factor: 5.742

3.  Endoscopic and histological features of mycophenolate mofetil colitis in patients after solid organ transplantation.

Authors:  Fernando H Calmet; Andres J Yarur; Geetha Pukazhendhi; Jawad Ahmad; Kalyan R Bhamidimarri
Journal:  Ann Gastroenterol       Date:  2015 Jul-Sep
  3 in total

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