Literature DB >> 23451996

Synthesis of the C1-C11 western fragment of madeirolide A.

Ian Paterson1, Gregory W Haslett.   

Abstract

The stereocontrolled synthesis of a fully elaborated C1-11 subunit of madeirolide A is described, utilizing an asymmetric boron aldol reaction and a cis-selective hetero-Michael cyclization to form the tetrahydropyran ring, followed by efficient formation of the required C5 α-glycoside.

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Year:  2013        PMID： 23451996     DOI： 10.1021/ol400280b

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Synthetic Access to the Mandelalide Family of Macrolides: Development of an Anion Relay Chemistry Strategy.

Authors:  Minh H Nguyen; Masashi Imanishi; Taichi Kurogi; Xuemei Wan; Jane E Ishmael; Kerry L McPhail; Amos B Smith
Journal:  J Org Chem       Date:  2018-02-26       Impact factor: 4.354

Review 2.  Recent Advances in Drug Discovery from South African Marine Invertebrates.

Authors:  Michael T Davies-Coleman; Clinton G L Veale
Journal:  Mar Drugs       Date:  2015-10-14       Impact factor: 5.118

3.  The stereodivergent formation of 2,6-cis and 2,6-trans-tetrahydropyrans: experimental and computational investigation of the mechanism of a thioester oxy-Michael cyclization.

Authors:  Kristaps Ermanis; Yin-Ting Hsiao; Uğur Kaya; Alan Jeuken; Paul A Clarke
Journal:  Chem Sci       Date:  2016-08-30       Impact factor: 9.825

Review 4.  Synthetic efforts on the road to marine natural products bearing 4-O-2,3,4,6-tetrasubstituted THPs: an update.

Authors:  Marta Fariña-Ramos; Celina García; Víctor S Martín; Sergio J Álvarez-Méndez
Journal:  RSC Adv       Date:  2021-02-03       Impact factor: 3.361
  4 in total

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