Y Joseph Woo1, John W MacArthur. 1. Department of Surgery, Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA. wooy@uphs.upenn.edu
Abstract
OBJECTIVES: Mitral valve repair techniques for degenerative disease typically entail leaflet resection or neochordal construction, which may require extensive resection, leaflet detachment/reattachment, reliance on diseased native chords or precise neochordal measuring. Occasionally, impaired leaflet mobility, reduced coaptation surface and systolic anterior motion (SAM) may result. We describe a novel technique for addressing posterior leaflet prolapse/flail, which both simplifies repair and addresses these issues. METHODS: Fifty-four patients (age 62 ± 11 years) with degenerative MR underwent this new repair, 36 of whom minimally-invasively. A CV5 Gore-Tex suture was placed into the posterior left ventricular myocardium underneath the prolapsing segment as an anchor. This suture was then used to imbricate a portion of the prolapsed segment into the ventricle, creating a smooth, broad, non-prolapsed coapting surface on a leaflet with preserved mobility, additional neochordal support and posteriorly positioned enough to preclude SAM. RESULTS: Repair was successful in all patients. The mean MR grade was reduced from +3.8 to +0.1 with 50 of 54 patients having zero MR and 4 of the 54 having trace or mild MR. All patients had proper antero-posterior location of the coaptation line of a mean length of 10.2 mm, and preserved posterior leaflet mobility. No patients had SAM or mitral stenosis. All patients were discharged and are currently doing well. CONCLUSION: This new technique facilitated efficient single-suture repair of the prolapsed posterior leaflet mitral regurgitation without the need for resection or sliding annuloplasty. It precluded the need for precise neochordal measurement and preserved the leaflet coaptation surface.
OBJECTIVES: Mitral valve repair techniques for degenerative disease typically entail leaflet resection or neochordal construction, which may require extensive resection, leaflet detachment/reattachment, reliance on diseased native chords or precise neochordal measuring. Occasionally, impaired leaflet mobility, reduced coaptation surface and systolic anterior motion (SAM) may result. We describe a novel technique for addressing posterior leaflet prolapse/flail, which both simplifies repair and addresses these issues. METHODS: Fifty-four patients (age 62 ± 11 years) with degenerative MR underwent this new repair, 36 of whom minimally-invasively. A CV5 Gore-Tex suture was placed into the posterior left ventricular myocardium underneath the prolapsing segment as an anchor. This suture was then used to imbricate a portion of the prolapsed segment into the ventricle, creating a smooth, broad, non-prolapsed coapting surface on a leaflet with preserved mobility, additional neochordal support and posteriorly positioned enough to preclude SAM. RESULTS: Repair was successful in all patients. The mean MR grade was reduced from +3.8 to +0.1 with 50 of 54 patients having zero MR and 4 of the 54 having trace or mild MR. All patients had proper antero-posterior location of the coaptation line of a mean length of 10.2 mm, and preserved posterior leaflet mobility. No patients had SAM or mitral stenosis. All patients were discharged and are currently doing well. CONCLUSION: This new technique facilitated efficient single-suture repair of the prolapsed posterior leaflet mitral regurgitation without the need for resection or sliding annuloplasty. It precluded the need for precise neochordal measurement and preserved the leaflet coaptation surface.
Authors: S Nazari; F Carli; S Salvi; C Banfi; A Aluffi; Z Mourad; P Buniva; G Rescigno Journal: J Cardiovasc Surg (Torino) Date: 2000-04 Impact factor: 1.888
Authors: Eugene A Grossi; Aubrey C Galloway; Angelo LaPietra; Greg H Ribakove; Patricia Ursomanno; Julie Delianides; Alfred T Culliford; Costas Bizekis; Rick A Esposito; F Gregory Baumann; Marc S Kanchuger; Stephen B Colvin Journal: Ann Thorac Surg Date: 2002-09 Impact factor: 4.330
Authors: Wolfgang A Goetz; Hou-Sen Lim; Emmanuel Lansac; Hashim A Saber; Filip Pekar; Patricia A Weber; Carlos M G Duran Journal: J Heart Valve Dis Date: 2005-03
Authors: Maurice Enriquez-Sarano; Jean-François Avierinos; David Messika-Zeitoun; Delphine Detaint; Maryann Capps; Vuyisile Nkomo; Christopher Scott; Hartzell V Schaff; A Jamil Tajik Journal: N Engl J Med Date: 2005-03-03 Impact factor: 91.245
Authors: Filip P Casselman; Sam Van Slycke; Helge Dom; Dave L Lambrechts; Yvette Vermeulen; Hugo Vanermen Journal: J Thorac Cardiovasc Surg Date: 2003-02 Impact factor: 5.209
Authors: Annabel M Imbrie-Moore; Matthew H Park; Michael J Paulsen; Mark Sellke; Rohun Kulkami; Hanjay Wang; Yuanjia Zhu; Justin M Farry; Alexandra T Bourdillon; Christine Callinan; Haley J Lucian; Camille E Hironaka; Daniela Deschamps; Y Joseph Woo Journal: J R Soc Interface Date: 2020-12-02 Impact factor: 4.118
Authors: Andrew B Goldstone; Pavan Atluri; Wilson Y Szeto; Alen Trubelja; Jessica L Howard; John W MacArthur; Craig Newcomb; Joseph P Donnelly; Dale M Kobrin; Mary A Sheridan; Christiana Powers; Robert C Gorman; Joseph H Gorman; Alberto Pochettino; Joseph E Bavaria; Michael A Acker; W Clark Hargrove; Y Joseph Woo Journal: J Thorac Cardiovasc Surg Date: 2013-03 Impact factor: 5.209
Authors: Annabel M Imbrie-Moore; Yuanjia Zhu; Tabitha Bandy-Vizcaino; Matthew H Park; Robert J Wilkerson; Y Joseph Woo Journal: Ann Biomed Eng Date: 2021-11-03 Impact factor: 4.219
Authors: John W MacArthur; Jeffrey E Cohen; Andrew B Goldstone; Alexander S Fairman; Bryan B Edwards; Matthew A Hornick; Pavan Atluri; Y Joseph Woo Journal: Ann Thorac Surg Date: 2013-08-07 Impact factor: 4.330
Authors: Annabel M Imbrie-Moore; Michael J Paulsen; Yuanjia Zhu; Hanjay Wang; Haley J Lucian; Justin M Farry; John W MacArthur; Michael Ma; Y Joseph Woo Journal: J Thorac Cardiovasc Surg Date: 2020-02-19 Impact factor: 5.209
Authors: Annabel M Imbrie-Moore; Yuanjia Zhu; Matthew H Park; Michael J Paulsen; Hanjay Wang; Y Joseph Woo Journal: J Thorac Cardiovasc Surg Date: 2020-11-30 Impact factor: 6.439
Authors: Michael J Paulsen; Annabel M Imbrie-Moore; Hanjay Wang; Jung Hwa Bae; Camille E Hironaka; Justin M Farry; Haley J Lucian; Akshara D Thakore; John W MacArthur; Mark R Cutkosky; Y Joseph Woo Journal: Eur J Cardiothorac Surg Date: 2020-03-01 Impact factor: 4.191