| Literature DB >> 23449470 |
Abstract
Genome condensation during mitosis presents a chromatin landscape largely inaccessible to RNA polymerase II and most transcription factors. Caravaca et al. (2013) now report in Genes and Development that the pioneer transcription factor FOXA1 is retained at mitotic chromosomes, bookmarking the genome to enable gene expression reestablishment upon mitotic exit.Entities:
Year: 2013 PMID： 23449470 DOI： 10.1016/j.devcel.2013.02.005
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270