Literature DB >> 23449466

A bridge to understanding lipid droplet growth.

William A Prinz1.   

Abstract

Lipid droplets, storage sites of fatty acids and sterols, expand when excess lipids are converted to triacylglycerols. In this issue of Developmental Cell, Wilfling et al. (2013) show that this expansion relies on relocalization, via membrane bridges, of triacylglycerol-synthesizing enzymes from the ER to a subset of lipid droplets.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Year:  2013        PMID： 23449466      PMCID： PMC3751170          DOI： 10.1016/j.devcel.2013.02.004

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  4 in total

Review 1.  Lipid droplet formation on opposing sides of the endoplasmic reticulum.

Authors:  Stephen L Sturley; M Mahmood Hussain
Journal:  J Lipid Res       Date:  2012-06-14       Impact factor: 5.922

2.  Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets.

Authors:  Florian Wilfling; Huajin Wang; Joel T Haas; Natalie Krahmer; Travis J Gould; Aki Uchida; Ji-Xin Cheng; Morven Graham; Romain Christiano; Florian Fröhlich; Xinran Liu; Kimberly K Buhman; Rosalind A Coleman; Joerg Bewersdorf; Robert V Farese; Tobias C Walther
Journal:  Dev Cell       Date:  2013-02-14       Impact factor: 12.270

Review 3.  Not just fat: the structure and function of the lipid droplet.

Authors:  Toyoshi Fujimoto; Robert G Parton
Journal:  Cold Spring Harb Perspect Biol       Date:  2011-03-01       Impact factor: 10.005

Review 4.  Packaging of fat: an evolving model of lipid droplet assembly and expansion.

Authors:  Dawn L Brasaemle; Nathan E Wolins
Journal:  J Biol Chem       Date:  2011-11-16       Impact factor: 5.157
  4 in total
  6 in total

1.  COPI-TRAPPII activates Rab18 and regulates its lipid droplet association.

Authors:  Chunman Li; Xiaomin Luo; Shan Zhao; Gavin Ky Siu; Yongheng Liang; Hsiao Chang Chan; Ayano Satoh; Sidney Sb Yu
Journal:  EMBO J       Date:  2016-12-21       Impact factor: 11.598

Review 2.  Cellular cholesterol homeostasis and Alzheimer's disease.

Authors:  Ta-Yuan Chang; Yoshio Yamauchi; Mazahir T Hasan; Catherine Chang
Journal:  J Lipid Res       Date:  2017-03-15       Impact factor: 5.922

3.  CDP-DAG synthase 1 and 2 regulate lipid droplet growth through distinct mechanisms.

Authors:  Yanqing Xu; Hoi Yin Mak; Ivan Lukmantara; Yang E Li; Kyle L Hoehn; Xun Huang; Ximing Du; Hongyuan Yang
Journal:  J Biol Chem       Date:  2019-09-23       Impact factor: 5.157

4.  Mesoderm-specific transcript localization in the ER and ER-lipid droplet interface supports a role in adipocyte hypertrophy.

Authors:  Igor Prudovsky; Rea P Anunciado-Koza; Chester G Jacobs; Doreen Kacer; Matthew E Siviski; Robert A Koza
Journal:  J Cell Biochem       Date:  2017-12-04       Impact factor: 4.429

5.  Enteroviruses harness the cellular endocytic machinery to remodel the host cell cholesterol landscape for effective viral replication.

Authors:  Olha Ilnytska; Marianita Santiana; Nai-Yun Hsu; Wen-Li Du; Ying-Han Chen; Ekaterina G Viktorova; Georgy Belov; Anita Brinker; Judith Storch; Christopher Moore; Joseph L Dixon; Nihal Altan-Bonnet
Journal:  Cell Host Microbe       Date:  2013-09-11       Impact factor: 21.023

6.  Dietary S. maltophilia induces supersized lipid droplets by enhancing lipogenesis and ER-LD contacts in C. elegans.

Authors:  Kang Xie; Yangli Liu; Xixia Li; Hong Zhang; Shuyan Zhang; Ho Yi Mak; Pingsheng Liu
Journal:  Gut Microbes       Date:  2022 Jan-Dec
  6 in total

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