Literature DB >> 23449143

A one-two punch of miR-126/126* against metastasis.

Guangwen Ren1, Yibin Kang.   

Abstract

MicroRNAs regulate cancer metastasis by modulating both the intrinsic properties of tumour cells and their interactions with the tumour stroma. Both strands of the miR-126/miR-126* duplex are now shown to simultaneously target the Sdf-1α cytokine to reduce the recruitment of mesenchymal stem cells and inflammatory monocytes to primary tumours, thereby inhibiting lung metastasis.

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Year:  2013        PMID： 23449143     DOI： 10.1038/ncb2703

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  15 in total

1.  Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer.

Authors:  Kousuke Watanabe; Noriko Emoto; Emi Hamano; Mitsuhiro Sunohara; Masanori Kawakami; Hidenori Kage; Kentaro Kitano; Jun Nakajima; Akiteru Goto; Masashi Fukayama; Takahide Nagase; Yutaka Yatomi; Nobuya Ohishi; Daiya Takai
Journal:  Int J Cancer       Date:  2011-09-17       Impact factor: 7.396

2.  CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFα.

Authors:  Guangwen Ren; Xin Zhao; Ying Wang; Xin Zhang; Xiaodong Chen; Chunliang Xu; Zeng-rong Yuan; Arthur I Roberts; Liying Zhang; Betty Zheng; Ting Wen; Yanyan Han; Arnold B Rabson; Jay A Tischfield; Changshun Shao; Yufang Shi
Journal:  Cell Stem Cell       Date:  2012-11-15       Impact factor: 24.633

3.  A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells.

Authors:  Kim J Png; Nils Halberg; Mitsukuni Yoshida; Sohail F Tavazoie
Journal:  Nature       Date:  2011-12-14       Impact factor: 49.962

4.  The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation.

Authors:  Leon H Parker; Maike Schmidt; Suk-Won Jin; Alane M Gray; Dimitris Beis; Thinh Pham; Gretchen Frantz; Susan Palmieri; Kenneth Hillan; Didier Y R Stainier; Frederic J De Sauvage; Weilan Ye
Journal:  Nature       Date:  2004-04-15       Impact factor: 49.962

5.  miR-126 regulates angiogenic signaling and vascular integrity.

Authors:  Jason E Fish; Massimo M Santoro; Sarah U Morton; Sangho Yu; Ru-Fang Yeh; Joshua D Wythe; Kathryn N Ivey; Benoit G Bruneau; Didier Y R Stainier; Deepak Srivastava
Journal:  Dev Cell       Date:  2008-08       Impact factor: 12.270

6.  The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis.

Authors:  Shusheng Wang; Arin B Aurora; Brett A Johnson; Xiaoxia Qi; John McAnally; Joseph A Hill; James A Richardson; Rhonda Bassel-Duby; Eric N Olson
Journal:  Dev Cell       Date:  2008-08       Impact factor: 12.270

7.  miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.

Authors:  Yun Zhang; Pengyuan Yang; Tao Sun; Dong Li; Xin Xu; Yaocheng Rui; Chaoran Li; Mengyang Chong; Toni Ibrahim; Laura Mercatali; Dino Amadori; Xincheng Lu; Dong Xie; Qi-Jing Li; Xiao-Fan Wang
Journal:  Nat Cell Biol       Date:  2013-02-10       Impact factor: 28.824

8.  Endogenous human microRNAs that suppress breast cancer metastasis.

Authors:  Sohail F Tavazoie; Claudio Alarcón; Thordur Oskarsson; David Padua; Qiongqing Wang; Paula D Bos; William L Gerald; Joan Massagué
Journal:  Nature       Date:  2008-01-10       Impact factor: 49.962

9.  Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone.

Authors:  Xin Lu; Yibin Kang
Journal:  J Biol Chem       Date:  2009-08-31       Impact factor: 5.157

10.  Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells.

Authors:  Yoshimasa Saito; Jeffrey M Friedman; Yoshitomo Chihara; Gerda Egger; Jody C Chuang; Gangning Liang
Journal:  Biochem Biophys Res Commun       Date:  2008-12-29       Impact factor: 3.322
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  11 in total

Review 1.  Epigenetic alterations in human parathyroid tumors.

Authors:  Chiara Verdelli; Irene Forno; Valentina Vaira; Sabrina Corbetta
Journal:  Endocrine       Date:  2015-02-27       Impact factor: 3.633

2.  Differential expression of serum miR-126, miR-141 and miR-21 as novel biomarkers for early detection of liver metastasis in colorectal cancer.

Authors:  Jie Yin; Zhigang Bai; Jianning Song; Yun Yang; Jin Wang; Wei Han; Jun Zhang; Hua Meng; Xuemei Ma; Yao Yang; Tingting Wang; Weirong Li; Zhongtao Zhang
Journal:  Chin J Cancer Res       Date:  2014-02       Impact factor: 5.087

3.  Overexpression and knockout of miR-126 both promote leukemogenesis.

Authors:  Zejuan Li; Ping Chen; Rui Su; Yuanyuan Li; Chao Hu; Yungui Wang; Stephen Arnovitz; Miao He; Sandeep Gurbuxani; Zhixiang Zuo; Abdel G Elkahloun; Shenglai Li; Hengyou Weng; Hao Huang; Mary Beth Neilly; Shusheng Wang; Eric N Olson; Richard A Larson; Michelle M Le Beau; Jiwang Zhang; Xi Jiang; Minjie Wei; Jie Jin; Paul P Liu; Jianjun Chen
Journal:  Blood       Date:  2015-09-11       Impact factor: 22.113

Review 4.  MicroRNAs as pharmacological targets in diabetes.

Authors:  Yiping Mao; Ramkumar Mohan; Shungang Zhang; Xiaoqing Tang
Journal:  Pharmacol Res       Date:  2013-06-28       Impact factor: 7.658

5.  microRNAs Distinctively Regulate Vascular Smooth Muscle and Endothelial Cells: Functional Implications in Angiogenesis, Atherosclerosis, and In-Stent Restenosis.

Authors:  Gaetano Santulli
Journal:  Adv Exp Med Biol       Date:  2015       Impact factor: 2.622

6.  Prometastatic GPCR CD97 is a direct target of tumor suppressor microRNA-126.

Authors:  Ying Y Lu; Michael J Sweredoski; David Huss; Rusty Lansford; Sonja Hess; David A Tirrell
Journal:  ACS Chem Biol       Date:  2013-11-25       Impact factor: 5.100

7.  The regulation of tumor-suppressive microRNA, miR-126, in chronic lymphocytic leukemia.

Authors:  Daphne Guinn; Amy Lehman; Catherine Fabian; Lianbo Yu; Kami Maddocks; Leslie A Andritsos; Jeffrey A Jones; Joseph M Flynn; Samantha M Jaglowski; Jennifer A Woyach; John C Byrd; Amy J Johnson
Journal:  Cancer Med       Date:  2017-03-15       Impact factor: 4.452

8.  Exosomal miR-126 as a circulating biomarker in non-small-cell lung cancer regulating cancer progression.

Authors:  Franco Grimolizzi; Federica Monaco; Francesca Leoni; Massimo Bracci; Sara Staffolani; Cristiana Bersaglieri; Simona Gaetani; Matteo Valentino; Monica Amati; Corrado Rubini; Franca Saccucci; Jiri Neuzil; Marco Tomasetti; Lory Santarelli
Journal:  Sci Rep       Date:  2017-11-10       Impact factor: 4.379

Review 9.  MicroRNA-126: A new and promising player in lung cancer.

Authors:  Qijun Chen; Shuanghua Chen; Juanjuan Zhao; Ya Zhou; Lin Xu
Journal:  Oncol Lett       Date:  2020-11-12       Impact factor: 2.967

Review 10.  Role of Exosomal Noncoding RNAs in Lung Carcinogenesis.

Authors:  Tao Sun; Bill Kalionis; Guoying Lv; Shijin Xia; Wen Gao
Journal:  Biomed Res Int       Date:  2015-10-25       Impact factor: 3.411
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