Literature DB >> 23443974

Splenectomy in older adults: indications and clinical outcomes.

Lane L Frasier1, Preeti N Malani, Kathleen M Diehl.   

Abstract

The aim of this study was to improve the understanding of the indications and associated outcomes among older adults undergoing splenectomy. Data regarding patients of age ≥60 years treated between 1998 and 2008 were reviewed. Fifty patients (age 71.6 ± 8) were identified. Common indications for splenectomy included idiopathic thrombotic purpura (26.0 %) and lymphoma (28.0 %). Patient co-morbidities included hypertension (54 %), coronary artery disease (24 %) and diabetes mellitus (20 %). Twenty-seven patients (54 %) underwent laparoscopic surgery; 23 (46 %) had open procedures; more than half of open splenectomies were conversions from attempted laparoscopy. Mean post-operative length of stay (LOS) was 5.9 ± 5 days (range 1-21). Two patients died in hospital; an additional three died within 6 months. Five patients were discharged to an extended care facility (ECF). Three patients required readmission within 30 days. Increased age was associated with need for ECF (p = 0.01). Increasing LOS, but not age, was associated with 6-month mortality (p = 0.04). Although we noted a 10 % in hospital mortality rate, splenectomy appears to be safe for carefully selected older adults.

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Year:  2013        PMID: 23443974     DOI: 10.1007/s12185-013-1300-5

Source DB:  PubMed          Journal:  Int J Hematol        ISSN: 0925-5710            Impact factor:   2.490


  16 in total

1.  Frailty is associated with postoperative complications in older adults with medical problems.

Authors:  Monidipa Dasgupta; Darryl B Rolfson; Paul Stolee; Michael J Borrie; Mark Speechley
Journal:  Arch Gerontol Geriatr       Date:  2008-02-20       Impact factor: 3.250

2.  Functional status after colon cancer surgery in elderly nursing home residents.

Authors:  Emily Finlayson; Shoujun Zhao; W John Boscardin; Brant E Fries; C Seth Landefeld; R Adams Dudley
Journal:  J Am Geriatr Soc       Date:  2012-03-16       Impact factor: 5.562

3.  Impact of age on in-hospital mortality of surgical patients in a German university hospital.

Authors:  Andrej Udelnow; Steffen Leinung; Dierk Schreiter; Manfred Schönfelder; Peter Würl
Journal:  Arch Gerontol Geriatr       Date:  2005-06-29       Impact factor: 3.250

4.  Efficacy of splenectomy for patients with mantle cell non-Hodgkin's lymphoma.

Authors:  Y Yoong; P J Kurtin; C Allmer; S Geyer; T M Habermann; D M Nagorney; T E Witzig
Journal:  Leuk Lymphoma       Date:  2001 Nov-Dec

5.  Laparoscopic splenectomy for massive splenomegaly.

Authors:  Kent W Kercher; Brent D Matthews; R Matthew Walsh; Ronald F Sing; Charles L Backus; B Todd Heniford
Journal:  Am J Surg       Date:  2002-02       Impact factor: 2.565

6.  Laparoscopic splenectomy in patients with hematologic malignancies.

Authors:  R S Berman; A M Yahanda; P F Mansfield; M R Hemmila; J F Sweeney; G A Porter; M Kumparatana; B Leroux; R E Pollock; B W Feig
Journal:  Am J Surg       Date:  1999-12       Impact factor: 2.565

7.  Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery.

Authors:  Mary Beth Hamel; William G Henderson; Shukri F Khuri; Jennifer Daley
Journal:  J Am Geriatr Soc       Date:  2005-03       Impact factor: 5.562

8.  Extended esophagectomy in elderly patients with esophageal cancer: minor effect of age alone in determining the postoperative course and survival.

Authors:  B B Pultrum; D J Bosch; M W N Nijsten; M G G Rodgers; H Groen; J P J Slaets; J Th M Plukker
Journal:  Ann Surg Oncol       Date:  2010-02-24       Impact factor: 5.344

9.  Outcomes in octogenarians undergoing high-risk cancer operation: a national study.

Authors:  Emily Finlayson; Zhaohui Fan; John D Birkmeyer
Journal:  J Am Coll Surg       Date:  2007-10-01       Impact factor: 6.113

10.  Autoimmune hemolytic anemia as a risk factor of poor outcome in patients with splenic marginal zone lymphoma.

Authors:  Aniko Fodor; Miklos Zsolt Molnar; Laszlo Krenacs; Eniko Bagdi; Judit Csomor; Andras Matolcsy; Judit Demeter
Journal:  Pathol Oncol Res       Date:  2009-04-03       Impact factor: 3.201

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