Literature DB >> 23443798

FOX(M1) news--it is cancer.

Marianna Halasi1, Andrei L Gartel.   

Abstract

FOXM1 is an oncogenic transcription factor of the Forkhead family and it has a well-defined role in cell proliferation and cell-cycle progression. Expression of FOXM1 is excluded in quiescent or differentiated cells, but its level is highly elevated in proliferating and malignant cells. Overexpression of FOXM1 has been reported in more than 20 types of human cancer. In recent years, FOXM1 has been implicated in diverse cellular processes and also a growing body of experimental data has underlined the relevance of FOXM1 in tumorigenesis. Although FOXM1 is under the control of three major tumor suppressors (RB, p53, and p19(ARF)), it is still active in the majority of human cancers. The oncogenic potential of FOXM1 is mainly based on its ability to transcriptionally activate genes that are involved in different facets of cancer development. In this review, the contribution of FOXM1 to each of the hallmarks of cancer will be summarized and discussed.

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Year:  2013        PMID： 23443798      PMCID： PMC3596487          DOI： 10.1158/1535-7163.MCT-12-0712

Source DB:  PubMed          Journal:  Mol Cancer Ther        ISSN： 1535-7163            Impact factor:   6.261


  82 in total

1.  FoxM1 is required for execution of the mitotic programme and chromosome stability.

Authors:  Jamila Laoukili; Matthijs R H Kooistra; Alexandra Brás; Jos Kauw; Ron M Kerkhoven; Ashby Morrison; Hans Clevers; René H Medema
Journal:  Nat Cell Biol       Date:  2005-01-16       Impact factor: 28.824

2.  FOXM1c transactivates the human c-myc promoter directly via the two TATA boxes P1 and P2.

Authors:  Inken Wierstra; Jürgen Alves
Journal:  FEBS J       Date:  2006-09-11       Impact factor: 5.542

3.  The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells.

Authors:  Patricia A Madureira; Rana Varshochi; Demetra Constantinidou; Richard E Francis; R Charles Coombes; Kwok-Ming Yao; Eric W-F Lam
Journal:  J Biol Chem       Date:  2006-06-28       Impact factor: 5.157

4.  A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.

Authors:  Scott L Carter; Aron C Eklund; Isaac S Kohane; Lyndsay N Harris; Zoltan Szallasi
Journal:  Nat Genet       Date:  2006-08-20       Impact factor: 38.330

5.  FoxM1 in tumorigenicity of the neuroblastoma cells and renewal of the neural progenitors.

Authors:  Zebin Wang; Hyun Jung Park; Janai R Carr; Yi-ju Chen; Yu Zheng; Jing Li; Angela L Tyner; Robert H Costa; Srilata Bagchi; Pradip Raychaudhuri
Journal:  Cancer Res       Date:  2011-04-20       Impact factor: 12.701

6.  Induction of human epithelial stem/progenitor expansion by FOXM1.

Authors:  Emilios Gemenetzidis; Daniela Elena-Costea; Eric K Parkinson; Ahmad Waseem; Hong Wan; Muy-Teck Teh
Journal:  Cancer Res       Date:  2010-11-09       Impact factor: 12.701

7.  Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor.

Authors:  Vladimir V Kalinichenko; Michael L Major; Xinhe Wang; Vladimir Petrovic; Joseph Kuechle; Helena M Yoder; Margaret B Dennewitz; Brian Shin; Abhishek Datta; Pradip Raychaudhuri; Robert H Costa
Journal:  Genes Dev       Date:  2004-04-01       Impact factor: 11.361

8.  FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer.

Authors:  Richard E Francis; Stephen S Myatt; Janna Krol; Johan Hartman; Barrie Peck; Ursula B McGovern; Jun Wang; Stephanie K Guest; Aleksandra Filipovic; Ondrej Gojis; Carlo Palmieri; David Peston; Sami Shousha; Qunyan Yu; Piotr Sicinski; R Charles Coombes; Eric W-F Lam
Journal:  Int J Oncol       Date:  2009-07       Impact factor: 5.650

9.  The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer.

Authors:  Il-Man Kim; Timothy Ackerson; Sneha Ramakrishna; Maria Tretiakova; I-Ching Wang; Tanya V Kalin; Michael L Major; Galina A Gusarova; Helena M Yoder; Robert H Costa; Vladimir V Kalinichenko
Journal:  Cancer Res       Date:  2006-02-15       Impact factor: 12.701

10.  ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance.

Authors:  Julie Millour; Natalia de Olano; Yoshiya Horimoto; Lara J Monteiro; Julia K Langer; Rosa Aligue; Nabil Hajji; Eric W F Lam
Journal:  Mol Cancer Ther       Date:  2011-04-25       Impact factor: 6.261
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  99 in total

1.  The NF-κB genomic landscape in lymphoblastoid B cells.

Authors:  Bo Zhao; Luis A Barrera; Ina Ersing; Bradford Willox; Stefanie C S Schmidt; Hannah Greenfeld; Hufeng Zhou; Sarah B Mollo; Tommy T Shi; Kaoru Takasaki; Sizun Jiang; Ellen Cahir-McFarland; Manolis Kellis; Martha L Bulyk; Elliott Kieff; Benjamin E Gewurz
Journal:  Cell Rep       Date:  2014-08-21       Impact factor: 9.423

Review 2.  Targeting forkhead box M1 transcription factor in breast cancer.

Authors:  Ruth M O'Regan; Rita Nahta
Journal:  Biochem Pharmacol       Date:  2018-05-31       Impact factor: 5.858

3.  Targeting FOXM1 auto-regulation in cancer.

Authors:  Andrei L Gartel
Journal:  Cancer Biol Ther       Date:  2015       Impact factor: 4.742

4.  Nuclear FOXM1 drives chemoresistance in AML.

Authors:  I Khan; M Halasi; M F Zia; P Gann; S Gaitonde; N Mahmud; A L Gartel
Journal:  Leukemia       Date:  2016-10-03       Impact factor: 11.528

5.  High-level SAE2 promotes malignant phenotype and predicts outcome in gastric cancer.

Authors:  Duan-Fang Shao; Xiao-Hong Wang; Zi-Yu Li; Xiao-Fang Xing; Xiao-Jing Cheng; Ting Guo; Hong Du; Ying Hu; Bin Dong; Ning Ding; Lin Li; Shen Li; Qing-Da Li; Xian-Zi Wen; Lian-Hai Zhang; Jia-Fu Ji
Journal:  Am J Cancer Res       Date:  2015-01-15       Impact factor: 6.166

6.  Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.

Authors:  Alvaro Aytes; Antonina Mitrofanova; Celine Lefebvre; Mariano J Alvarez; Mireia Castillo-Martin; Tian Zheng; James A Eastham; Anuradha Gopalan; Kenneth J Pienta; Michael M Shen; Andrea Califano; Cory Abate-Shen
Journal:  Cancer Cell       Date:  2014-05-12       Impact factor: 31.743

7.  Association between FOXM1 and hedgehog signaling pathway in human cervical carcinoma by tissue microarray analysis.

Authors:  Hong Chen; Jingjing Wang; Hong Yang; Dan Chen; Panpan Li
Journal:  Oncol Lett       Date:  2016-08-02       Impact factor: 2.967

Review 8.  Fox transcription factors: from development to disease.

Authors:  Maria L Golson; Klaus H Kaestner
Journal:  Development       Date:  2016-12-15       Impact factor: 6.868

9.  Hsp70-Bag3 interactions regulate cancer-related signaling networks.

Authors:  Teresa A Colvin; Vladimir L Gabai; Jianlin Gong; Stuart K Calderwood; Hu Li; Suryaram Gummuluru; Olga N Matchuk; Svetlana G Smirnova; Nina V Orlova; Irina A Zamulaeva; Mikel Garcia-Marcos; Xiaokai Li; Z T Young; Jennifer N Rauch; Jason E Gestwicki; Shinichi Takayama; Michael Y Sherman
Journal:  Cancer Res       Date:  2014-07-03       Impact factor: 12.701

10.  Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells.

Authors:  Huajun Han; Laurie A Davidson; Yang-Yi Fan; Jennifer S Goldsby; Grace Yoon; Un-Ho Jin; Gus A Wright; Kerstin K Landrock; Bradley R Weeks; Rachel C Wright; Clinton D Allred; Arul Jayaraman; Ivan Ivanov; Jatin Roper; Stephen H Safe; Robert S Chapkin
Journal:  EMBO J       Date:  2020-08-10       Impact factor: 11.598
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