Literature DB >> 2344348

Genetic variation and biochemical properties of esterase-18 (ES-18) in the laboratory rat (Rattus norvegicus): a new locus of esterase cluster 2 in linkage group V.

R Kluge1, H J Hedrich, O von Deimling.   

Abstract

A new liver-specific rat carboxylesterase isozyme (EC 3.1.1.1) designated esterase-18 (ES-18) is described. Genetic variation of ES-18 was examined in 93 inbred strains and substrains and a structural locus Es-18 was suggested, coding for either the presence (Es-18a) or the absence (Es-18b) of the isozyme. Linkage studies involving two backcross series revealed that Es-18 resides in cluster 2 of LGV. No recombination between Es-18 and other cluster 2 loci was found in 19 lines of two RI strain sets or in the backcross series.

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Year:  1990        PMID： 2344348     DOI： 10.1007/bf00554821

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  14 in total

1.  Indigogenic staining methods for esterases.

Authors:  S J HOLT
Journal:  Gen Cytochem Methods       Date:  1958

2.  Serum esterase genetics in rats: two new alleles at Es-2, a new esterase regulated by hormonal factors, and linkage of these loci to the Ag-C blood group locus.

Authors:  D L Gasser; W K Silvers; H M Reynolds; G Black; J Palm
Journal:  Biochem Genet       Date:  1973-11       Impact factor: 1.890

3.  Esterase D: a new human polymorphism.

Authors:  D A Hopkinson; M A Mestriner; J Cortner; H Harris
Journal:  Ann Hum Genet       Date:  1973-10       Impact factor: 1.670

4.  Immunochemical characterization of esterase active antigens in rat liver microsomes.

Authors:  J Anner; M Raftell
Journal:  Mol Immunol       Date:  1979-10       Impact factor: 4.407

5.  A genetically controlled esterase in rat plasma.

Authors:  K B Augustinsson; B Henricson
Journal:  Biochim Biophys Acta       Date:  1966-08-24

6.  Esterase activities and soman toxicity in developing rat.

Authors:  S H Sterri; G Berge; F Fonnum
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1985-08

7.  Esterase-16 (ES-16) of the rat (Rattus norvegicus): identification and genetic characterization.

Authors:  O H von Deimling; B Simon; R Kluge; H Hedrich
Journal:  Biochem Genet       Date:  1988-10       Impact factor: 1.890

8.  Re-evaluation of LG V of the rat and assignment of 12 carboxylesterases to two gene clusters.

Authors:  H J Hedrich; O von Deimling
Journal:  J Hered       Date:  1987 Mar-Apr       Impact factor: 2.645

9.  Gonadal hormone-induced changes in hepatic microsomal carboxylesterase in rats.

Authors:  M Hosokawa; T Satoh; S Ohkawara; S Ohmori; T Igarashi; K Ueno; H Kitagawa
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1984-11

10.  Biochemical genetics of Es-14 (formerly Es-Si) and a new esterase variation, Es-15, of the laboratory rat (Rattus norvegicus): biochemistry, tissue expression, and linkage to Es-1 in linkage group V.

Authors:  H J Hedrich; O von Deimling; R Kluge
Journal:  Biochem Genet       Date:  1987-02       Impact factor: 1.890
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