Literature DB >> 23441787

Stimulating the discussion on saliva substitutes: a clinical perspective.

F Dost1, C S Farah.   

Abstract

Xerostomia is a significant problem commonly faced by patients and oral health practitioners. There is no cure for this condition, which commonly manifests as a side effect of medications, head and neck irradiation and other systemic conditions, such as Sjögren's syndrome and type 2 diabetes. It may also arise idiopathically. Therefore, treatment is palliative and takes the form of oral lubricants and saliva substitutes which aim to reduce symptoms associated with xerostomia as well as prevent oral disease secondary to it. Recently there has been an expansion of the number and range of products available in Australia for the palliative management of xerostomia. It is imperative then that oral health professionals have a sound understanding of the advantages and disadvantages of using such products as patients tend to be well informed about new products which are commercially available. This article discusses some of the most commonly available products used for the symptomatic relief and preventive management of xerostomia. Amongst the plethora of products available to the patient suffering from xerostomia, no single product or product range adequately reproduces the properties of natural saliva and therefore consideration of patients' concerns, needs and oral health state should be taken into account when formulating a home care regime. With Australia's ageing population and its heavier reliance on medications and treatments which may induce xerostomia, oral health professionals are likely to encounter this condition more than ever before and therefore an understanding of xerostomia and its management is essential to patient care.
© 2013 Australian Dental Association.

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Year:  2013        PMID: 23441787     DOI: 10.1111/adj.12023

Source DB:  PubMed          Journal:  Aust Dent J        ISSN: 0045-0421            Impact factor:   2.291


  16 in total

1.  Palliative Care for Salivary Gland Dysfunction Highlights the Need for Regenerative Therapies: A Review on Radiation and Salivary Gland Stem Cells.

Authors:  Alejandro Martinez Chibly; Thao Nguyen; Kirsten H Limesand
Journal:  J Palliat Care Med       Date:  2014-08-06

2.  Specialized pro-resolving receptors are expressed in salivary glands with Sjögren's syndrome.

Authors:  Harim Tavares Dos Santos; Kihoon Nam; Frank Maslow; Bryan Trump; Olga J Baker
Journal:  Ann Diagn Pathol       Date:  2021-11-17       Impact factor: 2.090

3.  The Measurement of Contact Angle, pH, and Conductivity of Artificial Saliva and Mouthwashes on Enamel, Glass-Ionomer, and Composite Dental Materials.

Authors:  Saima Qureshi; Lazar Milić; Bojan Petrović; Marija Vejin; Sanja Kojić; Stefan Jarić; Goran Stojanović
Journal:  Materials (Basel)       Date:  2022-06-28       Impact factor: 3.748

4.  Post-Irradiated Human Submandibular Glands Display High Collagen Deposition, Disorganized Cell Junctions, and an Increased Number of Adipocytes.

Authors:  Kihoon Nam; Christina L Maruyama; Bryan G Trump; Luke Buchmann; Jason P Hunt; Marcus M Monroe; Olga J Baker
Journal:  J Histochem Cytochem       Date:  2016-04-28       Impact factor: 2.479

5.  SPM Receptor Expression and Localization in Irradiated Salivary Glands.

Authors:  Harim Tavares Dos Santos; Kihoon Nam; Jason P Hunt; Luke O Buchmann; Marcus M Monroe; Olga J Baker
Journal:  J Histochem Cytochem       Date:  2021-08       Impact factor: 4.137

6.  Label-retaining cells in the adult murine salivary glands possess characteristics of adult progenitor cells.

Authors:  Alejandro M Chibly; Lauren Querin; Zoey Harris; Kirsten H Limesand
Journal:  PLoS One       Date:  2014-09-19       Impact factor: 3.240

Review 7.  Radiation-induced dental caries, prevention and treatment - A systematic review.

Authors:  Nishtha Gupta; Manoj Pal; Sheh Rawat; Mandeep S Grewal; Himani Garg; Deepika Chauhan; Parveen Ahlawat; Sarthak Tandon; Ruparna Khurana; Anjali K Pahuja; Mayur Mayank; Bharti Devnani
Journal:  Natl J Maxillofac Surg       Date:  2015 Jul-Dec

8.  Oral Rehabilitation and Management for Secondary Sjögren's Syndrome in a Child.

Authors:  Tatiana Kelly da Silva Fidalgo; Carla Nogueira; Marcia Rejane Thomas Canabarro Andrade; Andrea Graciene Lopez Ramos Valente; Patricia Nivoloni Tannure
Journal:  Case Rep Dent       Date:  2016-11-27

9.  Efficacy of gel-based artificial saliva on Candida colonization and saliva properties in xerostomic post-radiotherapy head and neck cancer patients: a randomized controlled trial.

Authors:  Aroonwan Lam-Ubol; Oranart Matangkasombut; Dunyaporn Trachootham; Supanat Tarapan; Vanthana Sattabanasuk; Sineepat Talungchit; Wannaporn Paemuang; Tawaree Phonyiam; Orapin Chokchaitam; On-Ong Mungkung
Journal:  Clin Oral Investig       Date:  2020-08-10       Impact factor: 3.573

10.  Xerostomia after Radiotherapy for Oral and Oropharyngeal Cancer: Increasing Salivary Flow with Tasteless Sugar-free Chewing Gum.

Authors:  Julie Killerup Kaae; Lone Stenfeldt; Jesper Grau Eriksen
Journal:  Front Oncol       Date:  2016-05-03       Impact factor: 6.244

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