Literature DB >> 2344171

Randomized, double-blind trial of cefonicid and nafcillin in the treatment of skin and skin structure infections.

J S Daly1, M G Worthington, R J Andrews, R B Brown, R Schwartz, D J Sexton.   

Abstract

We compared treatment with one daily intravenous dose of cefonicid and multidose nafcillin in 65 patients with severe infections of the skin or skin structure. Clinical cure or improvement was achieved in 91% of the patients given cefonicid and in 87% of the patients given nafcillin (P = 0.97). The use of cefonicid may allow outpatient therapy of some severe infections.

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Year:  1990        PMID: 2344171      PMCID: PMC171660          DOI: 10.1128/AAC.34.4.654

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  5 in total

1.  Ceftriaxone treatment of skin and soft tissue infections in a once daily regimen.

Authors:  R W Bradsher; R M Snow
Journal:  Am J Med       Date:  1984-10-19       Impact factor: 4.965

2.  Once-daily ceftriaxone for skin and soft tissue infections.

Authors:  F M Gordin; C B Wofsy; J Mills
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

3.  Cefonicid kinetics in subjects with normal and impaired renal function.

Authors:  A D Blair; B M Maxwell; S C Forland; L Jacob; R E Cutler
Journal:  Clin Pharmacol Ther       Date:  1984-06       Impact factor: 6.875

4.  Comparison of cefonicid and cefazolin for treatment of soft-tissue infections.

Authors:  G Slutkin; J Marzouk; L Dall; J Mills
Journal:  Rev Infect Dis       Date:  1984 Nov-Dec

5.  Overview of bacterial infections of the skin and soft tissue and clinical experience with ticarcillin plus clavulanate potassium in their treatment.

Authors:  G A Pankey; H P Katner; G T Valainis; M J Clarkson; L M Cortez; J R Dalovisio
Journal:  Am J Med       Date:  1985-11-29       Impact factor: 4.965

  5 in total
  3 in total

1.  Noninferiority trial design and analysis with an ordered three-level categorical endpoint.

Authors:  Erica Brittain; Zonghui Hu
Journal:  J Biopharm Stat       Date:  2009-07       Impact factor: 1.051

Review 2.  A practical guide to the treatment of complicated skin and soft tissue infections.

Authors:  Horatio B Fung; Joanne Y Chang; Stephen Kuczynski
Journal:  Drugs       Date:  2003       Impact factor: 9.546

Review 3.  Interventions for cellulitis and erysipelas.

Authors:  Sally A Kilburn; Peter Featherstone; Bernie Higgins; Richard Brindle
Journal:  Cochrane Database Syst Rev       Date:  2010-06-16
  3 in total

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