Literature DB >> 2344037

Affinity of fibroblast growth factors for beta-cyclodextrin tetradecasulfate.

S N Yuen1, J Folkman, P B Weisz, M M Joullie, W R Ewing.   

Abstract

beta-Cyclodextrin tetradecasulfate was found to have a very strong affinity for fibroblast growth factor (FGF) and could substitute for heparin in FGF purification. Basic FGF was purified about 200,000-fold from a rat chondrosarcoma using a method of biaffinity chromatography in which the beta-cyclodextrin tetradecasulfate polymer was mixed with copper-Sepharose. This method takes advantage of the strong affinity of FGF for both beta-cyclodextrin tetradecasulfate and copper.

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Year:  1990        PMID： 2344037     DOI： 10.1016/0003-2697(90)90263-9

Source DB:  PubMed          Journal:  Anal Biochem        ISSN： 0003-2697            Impact factor:   3.365


  5 in total

1.  Duodenal ulcer. Discovery of a new mechanism and development of angiogenic therapy that accelerates healing.

Authors:  J Folkman; S Szabo; M Stovroff; P McNeil; W Li; Y Shing
Journal:  Ann Surg       Date:  1991-10       Impact factor: 12.969

2.  Incorporating β-cyclodextrin into collagen scaffolds to sequester growth factors and modulate mesenchymal stem cell activity.

Authors:  William K Grier; Aleczandria S Tiffany; Matthew D Ramsey; Brendan A C Harley
Journal:  Acta Biomater       Date:  2018-06-23       Impact factor: 8.947

3.  Sustained inhibition of intimal thickening. In vitro and in vivo effects of polymeric beta-cyclodextrin sulfate.

Authors:  W B Bachinsky; E S Barnathan; H Liu; S S Okada; A Kuo; P N Raghunath; M Muttreja; R J Caron; J E Tomaszewski; M A Golden
Journal:  J Clin Invest       Date:  1995-12       Impact factor: 14.808

4.  Inhibition of angiogenesis and tumor growth in the brain. Suppression of endothelial cell turnover by penicillamine and the depletion of copper, an angiogenic cofactor.

Authors:  S S Brem; D Zagzag; A M Tsanaclis; S Gately; M P Elkouby; S E Brien
Journal:  Am J Pathol       Date:  1990-11       Impact factor: 4.307

5.  Domains of neuronal heparan sulphate proteoglycans involved in neurite growth on laminin.

Authors:  K E Dow; R J Riopelle; R Kisilevsky
Journal:  Cell Tissue Res       Date:  1991-08       Impact factor: 5.249
  5 in total

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