| Literature DB >> 23439932 |
Chuan Fu1, Xueyun Zheng, Yao Jiang, Yan Liu, Pengxiang Xu, Zhiping Zeng, Rihe Liu, Yufen Zhao.
Abstract
We have synthesized γ-[(18)O4]-ATP and used it to develop a non-radioactive and multiplex method. Significantly, this novel approach can be applied to any kinases without using a purified enzyme or a fluorescent substrate. Using this approach, the effectiveness and specificity of inhibitors on several kinases could be readily determined.Entities:
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Year: 2013 PMID： 23439932 DOI： 10.1039/c3cc38467e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222