INTRODUCTION: Identifying reperfusion and predicting post procedure risk is important following Percutaneous Coronary Interventions (PCI). An Angiographic Perfusion Score (APS) combining TIMI flow (TFG) and myocardial perfusion (TMPG) grades before and after PCI can accurately measure both epicardial and myocardial perfusion and predict Major Adverse Cardiac Events (MACE). PATIENTS AND METHODS: APS was calculated in 226 (88 ST elevation Myocardial Infarction (STEMI) and 138 Non STEMI) patients. Maximum score being 12, reperfusion was defined as failed: 0-3, partial: 4-9, and full APS: 10-12. Thirty day MACE were observed. RESULTS: APS identified reperfusion significantly more than TMPG alone (STEMI: 50.6% vs 11.8% (p < 0.001); Non STEMI, early reperfusion: 69.4% vs 52.8% (p < 0.01) and Non STEMI late reperfusion: 38.2% vs 7.8%; (p ≤ 0.001) respectively. A significantly lower incidence of MACE was observed in the full as compared to the failed APS group (1.8% vs 22.5%) (p < 0.001). No differences were noted between TMPG 0-2 (9.8%, 9.4%, 7.3%, respectively) (p = NS). CONCLUSION: Compared to MPG alone APS detects more low risk reperfused patients, post PCI.
INTRODUCTION: Identifying reperfusion and predicting post procedure risk is important following Percutaneous Coronary Interventions (PCI). An Angiographic Perfusion Score (APS) combining TIMI flow (TFG) and myocardial perfusion (TMPG) grades before and after PCI can accurately measure both epicardial and myocardial perfusion and predict Major Adverse Cardiac Events (MACE). PATIENTS AND METHODS: APS was calculated in 226 (88 ST elevation Myocardial Infarction (STEMI) and 138 Non STEMI) patients. Maximum score being 12, reperfusion was defined as failed: 0-3, partial: 4-9, and full APS: 10-12. Thirty day MACE were observed. RESULTS:APS identified reperfusion significantly more than TMPG alone (STEMI: 50.6% vs 11.8% (p < 0.001); Non STEMI, early reperfusion: 69.4% vs 52.8% (p < 0.01) and Non STEMI late reperfusion: 38.2% vs 7.8%; (p ≤ 0.001) respectively. A significantly lower incidence of MACE was observed in the full as compared to the failed APS group (1.8% vs 22.5%) (p < 0.001). No differences were noted between TMPG 0-2 (9.8%, 9.4%, 7.3%, respectively) (p = NS). CONCLUSION: Compared to MPG alone APS detects more low risk reperfused patients, post PCI.
Authors: C M Gibson; C P Cannon; S A Murphy; K A Ryan; R Mesley; S J Marble; C H McCabe; F Van De Werf; E Braunwald Journal: Circulation Date: 2000-01-18 Impact factor: 29.690
Authors: C M Gibson; S A Murphy; M J Rizzo; K A Ryan; S J Marble; C H McCabe; C P Cannon; F Van de Werf; E Braunwald Journal: Circulation Date: 1999-04-20 Impact factor: 29.690
Authors: C Michael Gibson; Christopher P Cannon; Sabina A Murphy; Susan J Marble; Hal V Barron; Eugene Braunwald Journal: Circulation Date: 2002-04-23 Impact factor: 29.690
Authors: Graham C Wong; David A Morrow; Sabina Murphy; Nicole Kraimer; Rupal Pai; David James; Debbie H Robertson; Laura A Demopoulos; Peter DiBattiste; Christopher P Cannon; C Michael Gibson Journal: Circulation Date: 2002-07-09 Impact factor: 29.690
Authors: Jose P S Henriques; Felix Zijlstra; Arnoud W J van 't Hof; Menko-Jan de Boer; Jan-Henk E Dambrink; Marcel Gosselink; Jan C A Hoorntje; Harry Suryapranata Journal: Circulation Date: 2003-04-14 Impact factor: 29.690
Authors: C Michael Gibson; Sabina A Murphy; David A Morrow; Julian M Aroesty; Raymond J Gibbons; Steven G Gourlay; Hal V Barron; Robert P Giugliano; Elliott M Antman; Eugene Braunwald Journal: Am Heart J Date: 2004-08 Impact factor: 4.749