BACKGROUND: The VitalPAC™ Early Warning Score (ViEWS) has an area under the receiver operator characteristic curve (AUROC) for death of acute unselected medical patients within 24h of 88% and the UK National Early Warning Scores is based on it. The score's discrimination has been validated on patients in the developed world, but nothing is known of its performance in resource-poor hospitals. METHODS: ViEWS was validated in 844 acutely ill medical patients admitted to Kitovu Hospital, Masaka, Uganda. RESULTS: The AUROC for death within 24h of admission was 88.6% (95% CI 82.5-94.7%). The inability to walk without help was found to be an additional independent predictor of in-hospital mortality, and ViEWS modified to include it had an AUROC for death within 24h of 91.9% (95% CI 86.5-97.2%). CONCLUSION: The discrimination of ViEWS in a resource poor sub-Saharan Africa hospital is the same as in the developed world. Inability to walk without help was found to be an additional independent predictor of mortality.
BACKGROUND: The VitalPAC™ Early Warning Score (ViEWS) has an area under the receiver operator characteristic curve (AUROC) for death of acute unselected medical patients within 24h of 88% and the UK National Early Warning Scores is based on it. The score's discrimination has been validated on patients in the developed world, but nothing is known of its performance in resource-poor hospitals. METHODS: ViEWS was validated in 844 acutely ill medical patients admitted to Kitovu Hospital, Masaka, Uganda. RESULTS: The AUROC for death within 24h of admission was 88.6% (95% CI 82.5-94.7%). The inability to walk without help was found to be an additional independent predictor of in-hospital mortality, and ViEWS modified to include it had an AUROC for death within 24h of 91.9% (95% CI 86.5-97.2%). CONCLUSION: The discrimination of ViEWS in a resource poor sub-Saharan Africa hospital is the same as in the developed world. Inability to walk without help was found to be an additional independent predictor of mortality.
Authors: Christopher C Moore; Riley Hazard; Kacie J Saulters; John Ainsworth; Susan A Adakun; Abdallah Amir; Ben Andrews; Mary Auma; Tim Baker; Patrick Banura; John A Crump; Martin P Grobusch; Michaëla A M Huson; Shevin T Jacob; Olamide D Jarrett; John Kellett; Shabir Lakhi; Albert Majwala; Martin Opio; Matthew P Rubach; Jamie Rylance; W Michael Scheld; John Schieffelin; Richard Ssekitoleko; India Wheeler; Laura E Barnes Journal: BMJ Glob Health Date: 2017-07-28
Authors: Stephen Gerry; Timothy Bonnici; Jacqueline Birks; Shona Kirtley; Pradeep S Virdee; Peter J Watkinson; Gary S Collins Journal: BMJ Date: 2020-05-20
Authors: Manuela Carugati; Helen L Zhang; Kajiru G Kilonzo; Michael J Maze; Venance P Maro; Matthew P Rubach; John A Crump Journal: Am J Trop Med Hyg Date: 2018-11 Impact factor: 2.345