Literature DB >> 23435750

Pharmacy and self-report adherence measures to predict virological outcomes for patients on free antiretroviral therapy in Tamil Nadu, India.

James H McMahon1, Anand Manoharan, Christine A Wanke, Shoba Mammen, Hepsibah Jose, Thabeetha Malini, Tony Kadavanu, Michael R Jordan, Julian H Elliott, Sharon R Lewin, Dilip Mathai.   

Abstract

Over 480,000 individuals receive free antiretroviral therapy (ART) in India yet data associating ART adherence with HIV viral load for populations exclusively receiving free ART are not available. Additionally estimates of adherence using pharmacy data on ART pick-up are not available for any population in India. After 12-months ART we found self-reported estimates of adherence were not associated with HIV viral load. Individuals with <100% adherence using pharmacy data predicted HIV viral load, and estimates combining pharmacy data and self-report were also predictive. Pharmacy adherence measures proved a feasible method to estimate adherence in India and appear more predictive of virological outcomes than self-report. Predictive adherence measures identified in this study warrant further investigation in populations receiving free ART in India to allow for identification of individuals at risk of virological failure and in need of adherence support.

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Year:  2013        PMID： 23435750      PMCID： PMC3674125          DOI： 10.1007/s10461-013-0436-x

Source DB:  PubMed          Journal:  AIDS Behav        ISSN： 1090-7165


  32 in total

1.  Suboptimal adherence associated with virological failure and resistance mutations to first-line highly active antiretroviral therapy (HAART) in Bangalore, India.

Authors:  Maria L Ekstrand; Anita Shet; Sara Chandy; Girija Singh; Ranjani Shamsundar; Vidya Madhavan; Shanmugam Saravanan; Elsa Heylen; Nagalingeswaran Kumarasamy
Journal:  Int Health       Date:  2011-03       Impact factor: 2.473

2.  Adherence to highly active antiretroviral therapy assessed by pharmacy claims predicts survival in HIV-infected South African adults.

Authors:  Jean B Nachega; Michael Hislop; David W Dowdy; Melanie Lo; Saad B Omer; Leon Regensberg; Richard E Chaisson; Gary Maartens
Journal:  J Acquir Immune Defic Syndr       Date:  2006-09       Impact factor: 3.731

3.  Pharmacy adherence measures to assess adherence to antiretroviral therapy: review of the literature and implications for treatment monitoring.

Authors:  James H McMahon; Michael R Jordan; Karen Kelley; Silvia Bertagnolio; Steven Y Hong; Christine A Wanke; Sharon R Lewin; Julian H Elliott
Journal:  Clin Infect Dis       Date:  2011-01-18       Impact factor: 9.079

4.  Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: the AACTG adherence instruments. Patient Care Committee & Adherence Working Group of the Outcomes Committee of the Adult AIDS Clinical Trials Group (AACTG).

Authors:  M A Chesney; J R Ickovics; D B Chambers; A L Gifford; J Neidig; B Zwickl; A W Wu
Journal:  AIDS Care       Date:  2000-06

5.  Adherence to nonnucleoside reverse transcriptase inhibitor-based HIV therapy and virologic outcomes.

Authors:  Jean B Nachega; Michael Hislop; David W Dowdy; Richard E Chaisson; Leon Regensberg; Gary Maartens
Journal:  Ann Intern Med       Date:  2007-04-17       Impact factor: 25.391

6.  Sensitivity and specificity of using CD4+ measurement and clinical evaluation to determine antiretroviral treatment failure in Thailand.

Authors:  Romanee Chaiwarith; Charussri Wachirakaphan; Wilai Kotarathititum; Jutharat Praparatanaphan; Thira Sirisanthana; Khuanchai Supparatpinyo
Journal:  Int J Infect Dis       Date:  2007-02-28       Impact factor: 3.623

7.  Measuring adherence to antiretroviral therapy in a diverse population using a visual analogue scale.

Authors:  Thomas P Giordano; David Guzman; Richard Clark; Edwin D Charlebois; David R Bangsberg
Journal:  HIV Clin Trials       Date:  2004 Mar-Apr

Review 8.  Preventing HIV antiretroviral resistance through better monitoring of treatment adherence.

Authors:  David R Bangsberg
Journal:  J Infect Dis       Date:  2008-05-15       Impact factor: 5.226

9.  High rates of adherence and treatment success in a public and public-private HIV clinic in India: potential benefits of standardized national care delivery systems.

Authors:  Anita Shet; Ayesha DeCosta; Elsa Heylen; Suresh Shastri; Sara Chandy; Maria Ekstrand
Journal:  BMC Health Serv Res       Date:  2011-10-17       Impact factor: 2.655

10.  Adherence to first-line antiretroviral therapy affects non-virologic outcomes among patients on treatment for more than 12 months in Lusaka, Zambia.

Authors:  Benjamin H Chi; Ronald A Cantrell; Isaac Zulu; Lloyd B Mulenga; Jens W Levy; Bushimbwa C Tambatamba; Stewart Reid; Albert Mwango; Alwyn Mwinga; Marc Bulterys; Michael S Saag; Jeffrey S A Stringer
Journal:  Int J Epidemiol       Date:  2009-02-17       Impact factor: 7.196
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  11 in total

1.  Patient-Initiated Repackaging of Antiretroviral Therapy, Viral Suppression and Drug Resistance.

Authors:  Habib O Ramadhani; Charles Muiruri; Venance P Maro; Balthazar Nyombi; Michael Omondi; Julian B Mushi; Eileen S Lirhunde; John A Bartlett
Journal:  AIDS Behav       Date:  2018-05

2.  Super Learner Analysis of Electronic Adherence Data Improves Viral Prediction and May Provide Strategies for Selective HIV RNA Monitoring.

Authors:  Maya L Petersen; Erin LeDell; Joshua Schwab; Varada Sarovar; Robert Gross; Nancy Reynolds; Jessica E Haberer; Kathy Goggin; Carol Golin; Julia Arnsten; Marc I Rosen; Robert H Remien; David Etoori; Ira B Wilson; Jane M Simoni; Judith A Erlen; Mark J van der Laan; Honghu Liu; David R Bangsberg
Journal:  J Acquir Immune Defic Syndr       Date:  2015-05-01       Impact factor: 3.731

3.  Antiretroviral therapy adherence measurement in non-clinical settings in South India.

Authors:  Nora J Kleinman; Lisa E Manhart; Rani Mohanraj; Shuba Kumar; Lakshmanan Jeyaseelan; Deepa Rao; Jane M Simoni
Journal:  AIDS Care       Date:  2014-08-14

Review 4.  Accuracy of measures for antiretroviral adherence in people living with HIV.

Authors:  Rhodine Smith; Gemma Villanueva; Katrin Probyn; Yanina Sguassero; Nathan Ford; Catherine Orrell; Karen Cohen; Marty Chaplin; Mariska Mg Leeflang; Paul Hine
Journal:  Cochrane Database Syst Rev       Date:  2022-07-25

5.  Durable HIV RNA resuppression after virologic failure while remaining on a first-line regimen: a cohort study.

Authors:  Christopher J Hoffmann; Salome Charalambous; Alison D Grant; Lynn Morris; Gavin J Churchyard; Richard E Chaisson
Journal:  Trop Med Int Health       Date:  2014-02       Impact factor: 2.622

6.  Current drug use and lack of HIV virologic suppression: point-of-care urine drug screen versus self-report.

Authors:  Han-Zhu Qian; Valerie J Mitchell; Sally Bebawy; Holly Cassell; Gina Perez; Catherine C McGowan; Timothy R Sterling; Sten H Vermund; Richard D'Aquila; Todd Hulgan
Journal:  BMC Infect Dis       Date:  2014-09-18       Impact factor: 3.090

7.  Development of an electronic medical record based alert for risk of HIV treatment failure in a low-resource setting.

Authors:  Nancy Puttkammer; Steven Zeliadt; Jean Gabriel Balan; Janet Baseman; Rodney Destiné; Jean Wysler Domerçant; Garilus France; Nathaelf Hyppolite; Valérie Pelletier; Nernst Atwood Raphael; Kenneth Sherr; Krista Yuhas; Scott Barnhart
Journal:  PLoS One       Date:  2014-11-12       Impact factor: 3.240

8.  Adherence to Antiretroviral Therapy and Virologic Failure: A Meta-Analysis.

Authors:  Woldesellassie M Bezabhe; Leanne Chalmers; Luke R Bereznicki; Gregory M Peterson
Journal:  Medicine (Baltimore)       Date:  2016-04       Impact factor: 1.889

9.  Clinical Benefits and Cost-Effectiveness of Laboratory Monitoring Strategies to Guide Antiretroviral Treatment Switching in India.

Authors:  Kenneth A Freedberg; Nagalingeswaran Kumarasamy; Ethan D Borre; Eric L Ross; Kenneth H Mayer; Elena Losina; Soumya Swaminathan; Timothy P Flanigan; Rochelle P Walensky
Journal:  AIDS Res Hum Retroviruses       Date:  2018-05-03       Impact factor: 1.723

10.  Factors associated with suboptimal adherence to antiretroviral therapy in Asia.

Authors:  Awachana Jiamsakul; Nagalingeswaran Kumarasamy; Rossana Ditangco; Patrick C K Li; Praphan Phanuphak; Thira Sirisanthana; Somnuek Sungkanuparph; Pacharee Kantipong; Christopher K C Lee; Mahiran Mustafa; Tuti Merati; Adeeba Kamarulzaman; Thida Singtoroj; Matthew Law
Journal:  J Int AIDS Soc       Date:  2014-05-16       Impact factor: 5.396
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