Literature DB >> 23435431

Myocyte enhancer factor 2C in hematopoiesis and leukemia.

K Canté-Barrett1, R Pieters1, J P P Meijerink1.   

Abstract

MEF2C is a selectively expressed transcription factor involved in different transcriptional complexes. Originally identified as an essential regulator of muscle development, ectopic expression of MEF2C as a result of chromosomal rearrangements is now linked to leukemia. Specifically, high MEF2C expression has been linked to mixed lineage leukemia-rearranged acute myeloid leukemia as well as to the immature subgroup of T-cell acute lymphoblastic leukemia. This review focuses on the role of MEF2C in the hematopoietic system and on aberrant MEF2C expression in human leukemia.

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Year:  2013        PMID： 23435431     DOI： 10.1038/onc.2013.56

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  43 in total

1.  LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis.

Authors:  Tatsuya Morishima; Ann-Christin Krahl; Masoud Nasri; Yun Xu; Narges Aghaallaei; Betül Findik; Maksim Klimiankou; Malte Ritter; Marcus D Hartmann; Christian Johannes Gloeckner; Sylwia Stefanczyk; Christian Lindner; Benedikt Oswald; Regine Bernhard; Karin Hähnel; Ursula Hermanutz-Klein; Martin Ebinger; Rupert Handgretinger; Nicolas Casadei; Karl Welte; Maya Andre; Patrick Müller; Baubak Bajoghli; Julia Skokowa
Journal:  Blood       Date:  2019-07-31       Impact factor: 22.113

2.  Identification of Glycopeptides as Posttranslationally Modified Neoantigens in Leukemia.

Authors:  Stacy A Malaker; Sarah A Penny; Lora G Steadman; Paisley T Myers; Justin C Loke; Manoj Raghavan; Dina L Bai; Jeffrey Shabanowitz; Donald F Hunt; Mark Cobbold
Journal:  Cancer Immunol Res       Date:  2017-03-17       Impact factor: 11.151

3.  Identification of the Regulatory Elements and Target Genes of Megakaryopoietic Transcription Factor MEF2C.

Authors:  Xianguo Kong; Lin Ma; Edward Chen; Chad A Shaw; Leonard C Edelstein
Journal:  Thromb Haemost       Date:  2019-02-07       Impact factor: 5.249

4.  High Sensitivity Quantitative Proteomics Using Automated Multidimensional Nano-flow Chromatography and Accumulated Ion Monitoring on Quadrupole-Orbitrap-Linear Ion Trap Mass Spectrometer.

Authors:  Paolo Cifani; Alex Kentsis
Journal:  Mol Cell Proteomics       Date:  2017-08-18       Impact factor: 5.911

5.  miR-218 suppressed the growth of lung carcinoma by reducing MEF2D expression.

Authors:  Lei Song; Dan Li; Yingkai Zhao; Yue Gu; Dan Zhao; Xiang Li; Xiaoxue Bai; Ying Sun; Xiufang Zhang; Huijie Sun; Yan Wang; Liping Peng
Journal:  Tumour Biol       Date:  2015-09-26

6.  1,25-Dihydroxyvitamin D3 induces monocytic differentiation of human myeloid leukemia cells by regulating C/EBPβ expression through MEF2C.

Authors:  Ruifang Zheng; Xuening Wang; George P Studzinski
Journal:  J Steroid Biochem Mol Biol       Date:  2014-11-20       Impact factor: 4.292

7.  The control operated by the cell cycle machinery on MEF2 stability contributes to the downregulation of CDKN1A and entry into S phase.

Authors:  Eros Di Giorgio; Enrico Gagliostro; Andrea Clocchiatti; Claudio Brancolini
Journal:  Mol Cell Biol       Date:  2015-03-02       Impact factor: 4.272

8.  A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility.

Authors:  Darren A Cusanovich; Andrew J Hill; Delasa Aghamirzaie; Riza M Daza; Hannah A Pliner; Joel B Berletch; Galina N Filippova; Xingfan Huang; Lena Christiansen; William S DeWitt; Choli Lee; Samuel G Regalado; David F Read; Frank J Steemers; Christine M Disteche; Cole Trapnell; Jay Shendure
Journal:  Cell       Date:  2018-08-02       Impact factor: 41.582

9.  Defective quorum sensing of acute lymphoblastic leukemic cells: evidence of collective behavior of leukemic populations as semi-autonomous aberrant ecosystems.

Authors:  Sapan J Patel; Su Dao; Costel C Darie; Bayard D Clarkson
Journal:  Am J Cancer Res       Date:  2016-06-01       Impact factor: 6.166

10.  The involvement of myocyte enhancer factor 2D in regulating tumor biology of cardiac myxoma.

Authors:  Yufeng Huo; Qingjun Zhao; Cheng Wang; Fen Zhao; Yinghai Du; Wenyu Sun
Journal:  Tumour Biol       Date:  2015-11-12
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